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Comprehensive profiling of mRNA splicing indicates that GC content signals altered cassette exon inclusion in Ewing sarcoma

Ewing sarcoma (EwS) is a small round blue cell tumor and is the second most frequent pediatric bone cancer. 85% of EwS tumors express the fusion oncoprotein EWS-FLI1, the product of a t(11;22) reciprocal translocation. Prior work has indicated that transcription regulation alone does not fully descr...

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Detalles Bibliográficos
Autores principales:	Graham, Garrett T, Selvanathan, Saravana P, Zöllner, Stefan K, Stahl, Emily, Shlien, Adam, Caplen, Natasha J, Üren, Aykut, Toretsky, Jeffrey A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Standard Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759570/ https://www.ncbi.nlm.nih.gov/pubmed/35047826 http://dx.doi.org/10.1093/narcan/zcab052

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