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Time-spatial analysis of T cell receptor repertoire in esophageal squamous cell carcinoma patients treated with combined radiotherapy and PD-1 blockade

T cell receptor (TCR) repertoire as a biomarker for predicting immunotherapy efficiency has been widely studied. However, its dynamics during radiotherapy combined with PD-1 blockade is little known. Using paired tumor and blood samples from the phase Ib clinical study (NCT03222440), we investigate...

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Detalles Bibliográficos
Autores principales:	Yan, Cihui, Ma, Xiaoxue, Guo, Zhoubo, Wei, Xiaoying, Han, Dong, Zhang, Tian, Chen, Xi, Cao, Fuliang, Dong, Jie, Zhao, Gang, Gao, Xuan, Wang, Tao, Jiang, Yao, Wang, Ping, Pang, Qingsong, Zhang, Wencheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759588/ https://www.ncbi.nlm.nih.gov/pubmed/35036077 http://dx.doi.org/10.1080/2162402X.2022.2025668

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