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Active RB causes visible changes in nuclear organization

RB restricts G1/S progression by inhibiting E2F. Here, we show that sustained expression of active RB, and prolonged G1 arrest, causes visible changes in chromosome architecture that are not directly associated with E2F inhibition. Using FISH probes against two euchromatin RB-associated regions, two...

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Detalles Bibliográficos
Autores principales:	Krishnan, Badri, Yasuhara, Takaaki, Rumde, Purva, Stanzione, Marcello, Lu, Chenyue, Lee, Hanjun, Lawrence, Michael S., Zou, Lee, Nieman, Linda T., Sanidas, Ioannis, Dyson, Nicholas J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759594/ https://www.ncbi.nlm.nih.gov/pubmed/35019938 http://dx.doi.org/10.1083/jcb.202102144

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