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Effect of dexmedetomidine on cardiorespiratory regulation in spontaneously breathing adult rats

PURPOSE: We examined the cardiorespiratory effect of dexmedetomidine, an α(2)- adrenoceptor/imidazoline 1 (I(1)) receptor agonist, in spontaneously breathing adult rats. METHODS: Male rats (226−301 g, n = 49) under isoflurane anesthesia had their tail vein cannulated for drug administration and thei...

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Detalles Bibliográficos
Autores principales: Kitajima, Yoichiro, Hashizume, Nana Sato, Saiki, Chikako, Ide, Ryoji, Imai, Toshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759648/
https://www.ncbi.nlm.nih.gov/pubmed/35030204
http://dx.doi.org/10.1371/journal.pone.0262263