The role of itaconate in host defense and inflammation

Macrophages exposed to inflammatory stimuli including LPS undergo metabolic reprogramming to facilitate macrophage effector function. This metabolic reprogramming supports phagocytic function, cytokine release, and ROS production that are critical to protective inflammatory responses. The Krebs cycl...

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Detalles Bibliográficos
Autores principales: Peace, Christian G., O’Neill, Luke A.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Review Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759771/
https://www.ncbi.nlm.nih.gov/pubmed/35040439
http://dx.doi.org/10.1172/JCI148548

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759771/
https://www.ncbi.nlm.nih.gov/pubmed/35040439
http://dx.doi.org/10.1172/JCI148548

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