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Immune responses to CCAR1 and other dermatomyositis autoantigens are associated with attenuated cancer emergence

BACKGROUND: The temporal clustering of a cancer diagnosis with dermatomyositis (DM) onset is strikingly associated with autoantibodies against transcriptional intermediary factor 1-γ (TIF1-γ). Nevertheless, many patients with anti–TIF1-γ antibodies never develop cancer. We investigated whether addit...

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Detalles Bibliográficos
Autores principales:	Fiorentino, David F., Mecoli, Christopher A., Rosen, Matthew C., Chung, Lorinda S., Christopher-Stine, Lisa, Rosen, Antony, Casciola-Rosen, Livia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Clinical Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759791/ https://www.ncbi.nlm.nih.gov/pubmed/35040440 http://dx.doi.org/10.1172/JCI150201

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