Cargando…

How tetraspanin-mediated cell entry of SARS-CoV-2 can dysregulate the shedding of the ACE2 receptor by ADAM17

COVID-19, the respiratory infection caused by the novel coronavirus SARS-CoV-2, presents a clinical picture consistent with the dysregulation of many of the pathways mediated by the metalloprotease ADAM17. ADAM17 is a sheddase that plays a key role in the modulation of ACE2, the receptor which also...

Descripción completa

Detalles Bibliográficos
Autor principal:	Healy, Eamonn F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759804/ https://www.ncbi.nlm.nih.gov/pubmed/35063769 http://dx.doi.org/10.1016/j.bbrc.2022.01.038

Ejemplares similares

A model for COVID-19-induced dysregulation of ACE2 shedding by ADAM17
por: Healy, Eamonn F., et al.
Publicado: (2021)

The collectrin‐like part of the SARS‐CoV‐1 and ‐2 receptor ACE2 is shed by the metalloproteinases ADAM10 and ADAM17
por: Niehues, Rabea Victoria, et al.
Publicado: (2022)

Tetraspanin CD9 modulates ADAM17-mediated shedding of LR11 in leukocytes
por: Tsukamoto, Shokichi, et al.
Publicado: (2014)

ADAM17 knockdown mitigates while ADAM17 overexpression aggravates cardiac fibrosis and dysfunction via regulating ACE2 shedding and myofibroblast transformation
por: Cheng, Jing, et al.
Publicado: (2022)

Activation of Kinin B1R Upregulates ADAM17 and Results in ACE2 Shedding in Neurons
por: Parekh, Rohan Umesh, et al.
Publicado: (2020)

Dynamics of ADAM17-Mediated Shedding of ACE2 Applied to Pancreatic Islets of Male db/db Mice
por: Pedersen, Kim Brint, et al.
Publicado: (2015)

Regulation of A disintegrin and metalloproteinase (ADAM) family sheddases ADAM10 and ADAM17: The emerging role of tetraspanins and rhomboids
por: Matthews, Alexandra L., et al.
Publicado: (2017)

miR-145 Alleviates Smooth Muscle Cell Phenotype Transition via ADAM17-Mediated ACE2 Shedding
por: Wen, Juan, et al.
Publicado: (2023)

ADAM10 and ADAM17 promote SARS‐CoV‐2 cell entry and spike protein‐mediated lung cell fusion
por: Jocher, Georg, et al.
Publicado: (2022)

LRP1 shedding in human brain: roles of ADAM10 and ADAM17
por: Liu, Qiang, et al.
Publicado: (2009)

ADAM17-Mediated Shedding of Inflammatory Cytokines in Hypertension
por: de Queiroz, Thyago M., et al.
Publicado: (2020)

Distinct roles for ADAM10 and ADAM17 in ectodomain shedding of six EGFR ligands
por: Sahin, Umut, et al.
Publicado: (2004)

P38 MAPK activated ADAM17 mediates ACE2 shedding and promotes cardiac remodeling and heart failure after myocardial infarction
por: Chen, Qi, et al.
Publicado: (2023)

The Correlation Between Immune Invasion and SARS-COV-2 Entry Protein ADAM17 in Cancer Patients by Bioinformatic Analysis
por: Wang, Kai, et al.
Publicado: (2022)

Tumor Necrosis Factor-α Convertase (ADAM17) Mediates Regulated Ectodomain Shedding of the Severe-acute Respiratory Syndrome-Coronavirus (SARS-CoV) Receptor, Angiotensin-converting Enzyme-2 (ACE2)
por: Lambert, Daniel W., et al.
Publicado: (2005)

ADAM10 mediates shedding of carbonic anhydrase IX ectodomain non-redundantly to ADAM17
por: Zatovicova, Miriam, et al.
Publicado: (2022)

Lung ACE2 and ADAM17 in pulmonary arterial hypertension: Implications for COVID-19?
por: Pérez-Vizcaíno, Francisco
Publicado: (2020)

Tetraspanin CD9 affects HPV16 infection by modulating ADAM17 activity and the ERK signalling pathway
por: Mikuličić, Snježana, et al.
Publicado: (2020)

ADAM17 is essential for ectodomain shedding of the EGF‐receptor ligand amphiregulin
por: Hosur, Vishnu, et al.
Publicado: (2018)

Involvement of shedding induced by ADAM17 on the nitric oxide pathway in hypertension
por: da Silva, Mirelly Cunha, et al.
Publicado: (2022)

Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE
por: Cavadas, Miguel, et al.
Publicado: (2017)

ACE2: The Major Cell Entry Receptor for SARS-CoV-2
por: Scialo, Filippo, et al.
Publicado: (2020)

SARS-CoV-2 Entry: At the Crossroads of CD147 and ACE2
por: Fenizia, Claudio, et al.
Publicado: (2021)

SARS-CoV-2 cell entry beyond the ACE2 receptor
por: Alipoor, Shamila D., et al.
Publicado: (2022)

Tetraspanins: Architects of Viral Entry and Exit Platforms
por: Hantak, Michael P., et al.
Publicado: (2019)

ACE2/ADAM17/TMPRSS2 Interplay May Be the Main Risk Factor for COVID-19
por: Zipeto, Donato, et al.
Publicado: (2020)

Scissor sisters: regulation of ADAM10 by the TspanC8 tetraspanins
por: Matthews, Alexandra L., et al.
Publicado: (2017)

ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration
por: Reyat, Jasmeet S., et al.
Publicado: (2017)

Glycyrrhizin Inhibits SARS-CoV-2 Entry into Cells by Targeting ACE2
por: He, Ming-Feng, et al.
Publicado: (2022)

Differences in Shedding of the Interleukin-11 Receptor by the Proteases ADAM9, ADAM10, ADAM17, Meprin α, Meprin β and MT1-MMP
por: Sammel, Martin, et al.
Publicado: (2019)

Regulation of Leukocytes by TspanC8 Tetraspanins and the “Molecular Scissor” ADAM10
por: Matthews, Alexandra L., et al.
Publicado: (2018)

Regulation of ADAM10 by the TspanC8 Family of Tetraspanins and Their Therapeutic Potential
por: Harrison, Neale, et al.
Publicado: (2021)

Identification of critical determinants on ACE2 for SARS-CoV entry and development of a potent entry inhibitor
por: Han, Dong P., et al.
Publicado: (2006)

Control of SARS-CoV-2 infection by MT1-MMP-mediated shedding of ACE2
por: Guo, Xuanming, et al.
Publicado: (2022)

ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium
por: Ma, Xiang, et al.
Publicado: (2021)

ACE2: Evidence of role as entry receptor for SARS-CoV-2 and implications in comorbidities
por: Zamorano Cuervo, Natalia, et al.
Publicado: (2020)

MicroRNAs targeting the SARS-CoV-2 entry receptor ACE2 in cardiomyocytes
por: Lu, Dongchao, et al.
Publicado: (2020)

Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
por: Wang, Qihui, et al.
Publicado: (2020)

The Repurposed ACE2 Inhibitors: SARS-CoV-2 Entry Blockers of Covid-19
por: Ahmad, Iqrar, et al.
Publicado: (2021)

TRIM28 regulates SARS-CoV-2 cell entry by targeting ACE2
por: Wang, Yinfang, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_slpb1ro43cnb1uvqbuorirbtpe