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Perioperative Cardiac Arrest: A 3-Year Prospective Study from a Tertiary Care University Hospital

PURPOSE: Perioperative cardiac arrests (CAs) are a rare but catastrophic perioperative complication. Much about incidence, risk factors, and outcomes of such events are still unknown. This study investigated anesthesia-related CAs at a tertiary teaching hospital. METHODS: CA incidence within 24 hour...

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Autores principales: Aloweidi, Abdelkarim, Alghanem, Subhi, Bsisu, Isam, Ababneh, Omar, Alrabayah, Mustafa, Al-Zaben, Khaled, Qudaisat, Ibraheem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759986/
https://www.ncbi.nlm.nih.gov/pubmed/35046730
http://dx.doi.org/10.2147/DHPS.S332162
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author Aloweidi, Abdelkarim
Alghanem, Subhi
Bsisu, Isam
Ababneh, Omar
Alrabayah, Mustafa
Al-Zaben, Khaled
Qudaisat, Ibraheem
author_facet Aloweidi, Abdelkarim
Alghanem, Subhi
Bsisu, Isam
Ababneh, Omar
Alrabayah, Mustafa
Al-Zaben, Khaled
Qudaisat, Ibraheem
author_sort Aloweidi, Abdelkarim
collection PubMed
description PURPOSE: Perioperative cardiac arrests (CAs) are a rare but catastrophic perioperative complication. Much about incidence, risk factors, and outcomes of such events are still unknown. This study investigated anesthesia-related CAs at a tertiary teaching hospital. METHODS: CA incidence within 24 hours of anesthesia administration was prospectively identified from May 1, 2016 to April 31, 2019. Each CA was matched by four other cases without CA receiving anesthesia on the same date and under similar operating conditions. The CA cases were reviewed and assigned to one of three groups: anesthesia-related, anesthesia-contributing, and anesthesia not related. RESULTS: A total of 58,303 patients underwent 73,557 procedures under anesthesia during the study period. In sum, 27 CAs were reported for incidence of 3.7 per 10,000 anesthesia administrations (95% CI 2.3–5.1). Eleven CA were anesthesia-related for incidence of 1.5 per 10,000 anesthesia administrations. Four CA cases were anesthesia-contributing for incidence of 0.5 per 10,000 anesthesia administrations, while 53% of the anesthesia-related and -contributing CAs were due to respiratory problems. American Society of Anesthesiologists (ASA) physical status score, cardiovascular surgery, emergency surgery, and increased duration of surgery were significantly correlated with CA incidents when compared to the control group. ASA physical status score is an independent risk factor of the occurrence of perioperative CA (OR 7.6, 95% CI 2.6–22.4; P<0.001). CONCLUSION: Identifying factors associated with increased risk for anesthesia-related CA is of great importance in risk stratification for surgical patients. ASA physical status score was found to be a major factor in predicting perioperative CA, since patients with higher ASA scores had a statistically significant increased risk of CA. Therefore, extra precautions must be taken when dealing with unprepared patients who have uncontrolled medical illnesses, especially those who will be undergoing emergency surgery.
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spelling pubmed-87599862022-01-18 Perioperative Cardiac Arrest: A 3-Year Prospective Study from a Tertiary Care University Hospital Aloweidi, Abdelkarim Alghanem, Subhi Bsisu, Isam Ababneh, Omar Alrabayah, Mustafa Al-Zaben, Khaled Qudaisat, Ibraheem Drug Healthc Patient Saf Original Research PURPOSE: Perioperative cardiac arrests (CAs) are a rare but catastrophic perioperative complication. Much about incidence, risk factors, and outcomes of such events are still unknown. This study investigated anesthesia-related CAs at a tertiary teaching hospital. METHODS: CA incidence within 24 hours of anesthesia administration was prospectively identified from May 1, 2016 to April 31, 2019. Each CA was matched by four other cases without CA receiving anesthesia on the same date and under similar operating conditions. The CA cases were reviewed and assigned to one of three groups: anesthesia-related, anesthesia-contributing, and anesthesia not related. RESULTS: A total of 58,303 patients underwent 73,557 procedures under anesthesia during the study period. In sum, 27 CAs were reported for incidence of 3.7 per 10,000 anesthesia administrations (95% CI 2.3–5.1). Eleven CA were anesthesia-related for incidence of 1.5 per 10,000 anesthesia administrations. Four CA cases were anesthesia-contributing for incidence of 0.5 per 10,000 anesthesia administrations, while 53% of the anesthesia-related and -contributing CAs were due to respiratory problems. American Society of Anesthesiologists (ASA) physical status score, cardiovascular surgery, emergency surgery, and increased duration of surgery were significantly correlated with CA incidents when compared to the control group. ASA physical status score is an independent risk factor of the occurrence of perioperative CA (OR 7.6, 95% CI 2.6–22.4; P<0.001). CONCLUSION: Identifying factors associated with increased risk for anesthesia-related CA is of great importance in risk stratification for surgical patients. ASA physical status score was found to be a major factor in predicting perioperative CA, since patients with higher ASA scores had a statistically significant increased risk of CA. Therefore, extra precautions must be taken when dealing with unprepared patients who have uncontrolled medical illnesses, especially those who will be undergoing emergency surgery. Dove 2022-01-10 /pmc/articles/PMC8759986/ /pubmed/35046730 http://dx.doi.org/10.2147/DHPS.S332162 Text en © 2022 Aloweidi et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Original Research
Aloweidi, Abdelkarim
Alghanem, Subhi
Bsisu, Isam
Ababneh, Omar
Alrabayah, Mustafa
Al-Zaben, Khaled
Qudaisat, Ibraheem
Perioperative Cardiac Arrest: A 3-Year Prospective Study from a Tertiary Care University Hospital
title Perioperative Cardiac Arrest: A 3-Year Prospective Study from a Tertiary Care University Hospital
title_full Perioperative Cardiac Arrest: A 3-Year Prospective Study from a Tertiary Care University Hospital
title_fullStr Perioperative Cardiac Arrest: A 3-Year Prospective Study from a Tertiary Care University Hospital
title_full_unstemmed Perioperative Cardiac Arrest: A 3-Year Prospective Study from a Tertiary Care University Hospital
title_short Perioperative Cardiac Arrest: A 3-Year Prospective Study from a Tertiary Care University Hospital
title_sort perioperative cardiac arrest: a 3-year prospective study from a tertiary care university hospital
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759986/
https://www.ncbi.nlm.nih.gov/pubmed/35046730
http://dx.doi.org/10.2147/DHPS.S332162
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