GRK3 deficiency elicits brain immune activation and psychosis

The G protein-coupled receptor kinase (GRK) family member protein GRK3 has been linked to the pathophysiology of schizophrenia and bipolar disorder. Expression, as well as protein levels, of GRK3 are reduced in post-mortem prefrontal cortex of schizophrenia subjects. Here, we investigate functional...

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Detalles Bibliográficos
Autores principales: Sellgren, Carl M., Imbeault, Sophie, Larsson, Markus K., Oliveros, Alfredo, Nilsson, Ida A. K., Codeluppi, Simone, Orhan, Funda, Bhat, Maria, Tufvesson-Alm, Maximilian, Gracias, Jessica, Kegel, Magdalena E., Zheng, Yiran, Faka, Anthi, Svedberg, Marie, Powell, Susan B., Caldwell, Sorana, Kamenski, Mary E., Vawter, Marquis P., Schulmann, Anton, Goiny, Michel, Svensson, Camilla I., Hökfelt, Tomas, Schalling, Martin, Schwieler, Lilly, Cervenka, Simon, Choi, Doo-Sup, Landén, Mikael, Engberg, Göran, Erhardt, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760053/
https://www.ncbi.nlm.nih.gov/pubmed/33976392
http://dx.doi.org/10.1038/s41380-021-01106-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760053/
https://www.ncbi.nlm.nih.gov/pubmed/33976392
http://dx.doi.org/10.1038/s41380-021-01106-0

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