Accumbens D2-MSN hyperactivity drives antipsychotic-induced behavioral supersensitivity

Antipsychotic-induced dopamine supersensitivity, or behavioral supersensitivity, is a problematic consequence of long-term antipsychotic treatment characterized by the emergence of motor abnormalities, refractory symptoms, and rebound psychosis. The underlying mechanisms are unclear and no approache...

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Detalles Bibliográficos
Autores principales: Kruyer, Anna, Parrilla-Carrero, Jeffrey, Powell, Courtney, Brandt, Lasse, Gutwinski, Stefan, Angelis, Ariana, Chalhoub, Reda M., Jhou, Thomas C., Kalivas, Peter W., Amato, Davide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Immediate Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760070/
https://www.ncbi.nlm.nih.gov/pubmed/34349226
http://dx.doi.org/10.1038/s41380-021-01235-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760070/
https://www.ncbi.nlm.nih.gov/pubmed/34349226
http://dx.doi.org/10.1038/s41380-021-01235-6

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