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Accumbens D2-MSN hyperactivity drives antipsychotic-induced behavioral supersensitivity
Antipsychotic-induced dopamine supersensitivity, or behavioral supersensitivity, is a problematic consequence of long-term antipsychotic treatment characterized by the emergence of motor abnormalities, refractory symptoms, and rebound psychosis. The underlying mechanisms are unclear and no approache...
Autores principales: | Kruyer, Anna, Parrilla-Carrero, Jeffrey, Powell, Courtney, Brandt, Lasse, Gutwinski, Stefan, Angelis, Ariana, Chalhoub, Reda M., Jhou, Thomas C., Kalivas, Peter W., Amato, Davide |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760070/ https://www.ncbi.nlm.nih.gov/pubmed/34349226 http://dx.doi.org/10.1038/s41380-021-01235-6 |
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