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Roles of Polycomb complexes in regulating gene expression and chromatin structure in plants
The evolutionary conserved Polycomb Group (PcG) repressive system comprises two central protein complexes, PcG repressive complex 1 (PRC1) and PRC2. These complexes, through the incorporation of histone modifications on chromatin, have an essential role in the normal development of eukaryotes. In re...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760139/ https://www.ncbi.nlm.nih.gov/pubmed/35059633 http://dx.doi.org/10.1016/j.xplc.2021.100267 |
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author | Baile, Fernando Gómez-Zambrano, Ángeles Calonje, Myriam |
author_facet | Baile, Fernando Gómez-Zambrano, Ángeles Calonje, Myriam |
author_sort | Baile, Fernando |
collection | PubMed |
description | The evolutionary conserved Polycomb Group (PcG) repressive system comprises two central protein complexes, PcG repressive complex 1 (PRC1) and PRC2. These complexes, through the incorporation of histone modifications on chromatin, have an essential role in the normal development of eukaryotes. In recent years, a significant effort has been made to characterize these complexes in the different kingdoms, and despite there being remarkable functional and mechanistic conservation, some key molecular principles have diverged. In this review, we discuss current views on the function of plant PcG complexes. We compare the composition of PcG complexes between animals and plants, highlight the role of recently identified plant PcG accessory proteins, and discuss newly revealed roles of known PcG partners. We also examine the mechanisms by which the repression is achieved and how these complexes are recruited to target genes. Finally, we consider the possible role of some plant PcG proteins in mediating local and long-range chromatin interactions and, thus, shaping chromatin 3D architecture. |
format | Online Article Text |
id | pubmed-8760139 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-87601392022-01-19 Roles of Polycomb complexes in regulating gene expression and chromatin structure in plants Baile, Fernando Gómez-Zambrano, Ángeles Calonje, Myriam Plant Commun Review Article The evolutionary conserved Polycomb Group (PcG) repressive system comprises two central protein complexes, PcG repressive complex 1 (PRC1) and PRC2. These complexes, through the incorporation of histone modifications on chromatin, have an essential role in the normal development of eukaryotes. In recent years, a significant effort has been made to characterize these complexes in the different kingdoms, and despite there being remarkable functional and mechanistic conservation, some key molecular principles have diverged. In this review, we discuss current views on the function of plant PcG complexes. We compare the composition of PcG complexes between animals and plants, highlight the role of recently identified plant PcG accessory proteins, and discuss newly revealed roles of known PcG partners. We also examine the mechanisms by which the repression is achieved and how these complexes are recruited to target genes. Finally, we consider the possible role of some plant PcG proteins in mediating local and long-range chromatin interactions and, thus, shaping chromatin 3D architecture. Elsevier 2021-11-26 /pmc/articles/PMC8760139/ /pubmed/35059633 http://dx.doi.org/10.1016/j.xplc.2021.100267 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Review Article Baile, Fernando Gómez-Zambrano, Ángeles Calonje, Myriam Roles of Polycomb complexes in regulating gene expression and chromatin structure in plants |
title | Roles of Polycomb complexes in regulating gene expression and chromatin structure in plants |
title_full | Roles of Polycomb complexes in regulating gene expression and chromatin structure in plants |
title_fullStr | Roles of Polycomb complexes in regulating gene expression and chromatin structure in plants |
title_full_unstemmed | Roles of Polycomb complexes in regulating gene expression and chromatin structure in plants |
title_short | Roles of Polycomb complexes in regulating gene expression and chromatin structure in plants |
title_sort | roles of polycomb complexes in regulating gene expression and chromatin structure in plants |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760139/ https://www.ncbi.nlm.nih.gov/pubmed/35059633 http://dx.doi.org/10.1016/j.xplc.2021.100267 |
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