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Systematic review and meta-analysis of tumour microsatellite-instability status as a predictor of response to fluorouracil-based adjuvant chemotherapy in colorectal cancer

PURPOSE: Colorectal cancer (CRC) can be classified according to the chromosomal-instability pathway (a microsatellite-stable (MSS) pathway) and the microsatellite-instability (MSI) pathway. Adjuvant therapy after surgery in advanced CRC is usually based on fluoropyrimidine 5-fluorouracil (5-FU) alon...

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Detalles Bibliográficos
Autores principales:	Aggarwal, Nikhil, Quaglia, Alberto, McPhail, Mark J. W., Monahan, Kevin J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760189/ https://www.ncbi.nlm.nih.gov/pubmed/34677685 http://dx.doi.org/10.1007/s00384-021-04046-x

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