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Revisional Therapy for Recurrent Symptoms After Heller Myotomy for Achalasia
PURPOSE: Symptom recurrence after initial surgical management of esophageal achalasia occurs in 10–25% of patients. The aim of this study was to analyze safety and efficacy of revisional therapy after failed Heller myotomy (HM). METHODS: A retrospective review of a prospective database was performed...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760227/ https://www.ncbi.nlm.nih.gov/pubmed/34341888 http://dx.doi.org/10.1007/s11605-021-05098-8 |
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author | Milito, Pamela Siboni, Stefano Lovece, Andrea Andreatta, Erika Asti, Emanuele Bonavina, Luigi |
author_facet | Milito, Pamela Siboni, Stefano Lovece, Andrea Andreatta, Erika Asti, Emanuele Bonavina, Luigi |
author_sort | Milito, Pamela |
collection | PubMed |
description | PURPOSE: Symptom recurrence after initial surgical management of esophageal achalasia occurs in 10–25% of patients. The aim of this study was to analyze safety and efficacy of revisional therapy after failed Heller myotomy (HM). METHODS: A retrospective review of a prospective database was performed searching for patients with recurrent symptoms after primary surgical therapy for achalasia. Patients with previously failed HM were considered for the final analysis. The Foregut questionnaire, and the Atkinson and Eckardt scales were used to assess severity of symptoms. Objective investigations routinely included upper gastrointestinal endoscopy and barium swallow study. Redo treatments consisted of endoscopic pneumatic dilation (PD), laparoscopic HM, hybrid Ivor Lewis esophagectomy, or stapled cardioplasty. A yearly clinical and endoscopic follow-up was scheduled in all patients. RESULTS: Over a 20-year period, 26 patients with a median age of 66 years (IQR 19.5) underwent revisional therapy after failed HM for achalasia at a tertiary-care university hospital. The median time after index procedure was 10 years (IQR 21). Revisional therapy consisted of endoscopic pneumatic dilation (n=13), laparoscopic HM and fundoplication (n=10), esophagectomy (n=2), and stapled cardioplasty and fundoplication (n=1). Nine (34.6%) of these patients required further endoscopic or surgical treatments. There was no mortality, and the overall complication rate was 7.7%. At a median follow-up of 42 months (range 10–149), a significant decrease of dysphagia, regurgitation, chest pain, respiratory symptoms, and median Eckardt score (p<0.05) was noted. CONCLUSION: In specialized and multidisciplinary centers, revisional therapy for achalasia is feasible, safe, and effective. |
format | Online Article Text |
id | pubmed-8760227 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Springer US |
record_format | MEDLINE/PubMed |
spelling | pubmed-87602272022-01-26 Revisional Therapy for Recurrent Symptoms After Heller Myotomy for Achalasia Milito, Pamela Siboni, Stefano Lovece, Andrea Andreatta, Erika Asti, Emanuele Bonavina, Luigi J Gastrointest Surg Original Article PURPOSE: Symptom recurrence after initial surgical management of esophageal achalasia occurs in 10–25% of patients. The aim of this study was to analyze safety and efficacy of revisional therapy after failed Heller myotomy (HM). METHODS: A retrospective review of a prospective database was performed searching for patients with recurrent symptoms after primary surgical therapy for achalasia. Patients with previously failed HM were considered for the final analysis. The Foregut questionnaire, and the Atkinson and Eckardt scales were used to assess severity of symptoms. Objective investigations routinely included upper gastrointestinal endoscopy and barium swallow study. Redo treatments consisted of endoscopic pneumatic dilation (PD), laparoscopic HM, hybrid Ivor Lewis esophagectomy, or stapled cardioplasty. A yearly clinical and endoscopic follow-up was scheduled in all patients. RESULTS: Over a 20-year period, 26 patients with a median age of 66 years (IQR 19.5) underwent revisional therapy after failed HM for achalasia at a tertiary-care university hospital. The median time after index procedure was 10 years (IQR 21). Revisional therapy consisted of endoscopic pneumatic dilation (n=13), laparoscopic HM and fundoplication (n=10), esophagectomy (n=2), and stapled cardioplasty and fundoplication (n=1). Nine (34.6%) of these patients required further endoscopic or surgical treatments. There was no mortality, and the overall complication rate was 7.7%. At a median follow-up of 42 months (range 10–149), a significant decrease of dysphagia, regurgitation, chest pain, respiratory symptoms, and median Eckardt score (p<0.05) was noted. CONCLUSION: In specialized and multidisciplinary centers, revisional therapy for achalasia is feasible, safe, and effective. Springer US 2021-08-02 2022 /pmc/articles/PMC8760227/ /pubmed/34341888 http://dx.doi.org/10.1007/s11605-021-05098-8 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Article Milito, Pamela Siboni, Stefano Lovece, Andrea Andreatta, Erika Asti, Emanuele Bonavina, Luigi Revisional Therapy for Recurrent Symptoms After Heller Myotomy for Achalasia |
title | Revisional Therapy for Recurrent Symptoms After Heller Myotomy for Achalasia |
title_full | Revisional Therapy for Recurrent Symptoms After Heller Myotomy for Achalasia |
title_fullStr | Revisional Therapy for Recurrent Symptoms After Heller Myotomy for Achalasia |
title_full_unstemmed | Revisional Therapy for Recurrent Symptoms After Heller Myotomy for Achalasia |
title_short | Revisional Therapy for Recurrent Symptoms After Heller Myotomy for Achalasia |
title_sort | revisional therapy for recurrent symptoms after heller myotomy for achalasia |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760227/ https://www.ncbi.nlm.nih.gov/pubmed/34341888 http://dx.doi.org/10.1007/s11605-021-05098-8 |
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