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Surveillance of antimicrobial-resistant Escherichia coli in Sheltered dogs in the Kanto Region of Japan
There is a lack of an established antimicrobial resistance (AMR) surveillance system in animal welfare centers. Therefore, the AMR prevalence in shelter dogs is rarely known. Herein, we conducted a survey in animal shelters in Chiba and Kanagawa prefectures, in the Kanto Region, Japan, to ascertain...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760262/ https://www.ncbi.nlm.nih.gov/pubmed/35031646 http://dx.doi.org/10.1038/s41598-021-04435-w |
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author | Hata, Akihisa Fujitani, Noboru Ono, Fumiko Yoshikawa, Yasuhiro |
author_facet | Hata, Akihisa Fujitani, Noboru Ono, Fumiko Yoshikawa, Yasuhiro |
author_sort | Hata, Akihisa |
collection | PubMed |
description | There is a lack of an established antimicrobial resistance (AMR) surveillance system in animal welfare centers. Therefore, the AMR prevalence in shelter dogs is rarely known. Herein, we conducted a survey in animal shelters in Chiba and Kanagawa prefectures, in the Kanto Region, Japan, to ascertain the AMR status of Escherichia coli (E. coli) prevalent in shelter dogs. E. coli was detected in the fecal samples of all 61 and 77 shelter dogs tested in Chiba and Kanagawa, respectively. The AMR was tested against 20 antibiotics. E. coli isolates derived from 16.4% and 26.0% of samples from Chiba and Kanagawa exhibited resistance to at least one antibiotic, respectively. E. coli in samples from Chiba and Kanagawa prefectures were commonly resistant to ampicillin, piperacillin, streptomycin, kanamycin, tetracycline, and nalidixic acid; that from the Kanagawa Prefecture to cefazolin, cefotaxime, aztreonam, ciprofloxacin, and levofloxacin and that from Chiba Prefecture to chloramphenicol and imipenem. Multidrug-resistant bacteria were detected in 18 dogs from both regions; β-lactamase genes (blaTEM, blaDHA-1, blaCTX-M-9 group CTX-M-14), quinolone-resistance protein genes (qnrB and qnrS), and mutations in quinolone-resistance-determining regions (gyrA and parC) were detected. These results could partially represent the AMR data in shelter dogs in the Kanto Region of Japan. |
format | Online Article Text |
id | pubmed-8760262 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-87602622022-01-18 Surveillance of antimicrobial-resistant Escherichia coli in Sheltered dogs in the Kanto Region of Japan Hata, Akihisa Fujitani, Noboru Ono, Fumiko Yoshikawa, Yasuhiro Sci Rep Article There is a lack of an established antimicrobial resistance (AMR) surveillance system in animal welfare centers. Therefore, the AMR prevalence in shelter dogs is rarely known. Herein, we conducted a survey in animal shelters in Chiba and Kanagawa prefectures, in the Kanto Region, Japan, to ascertain the AMR status of Escherichia coli (E. coli) prevalent in shelter dogs. E. coli was detected in the fecal samples of all 61 and 77 shelter dogs tested in Chiba and Kanagawa, respectively. The AMR was tested against 20 antibiotics. E. coli isolates derived from 16.4% and 26.0% of samples from Chiba and Kanagawa exhibited resistance to at least one antibiotic, respectively. E. coli in samples from Chiba and Kanagawa prefectures were commonly resistant to ampicillin, piperacillin, streptomycin, kanamycin, tetracycline, and nalidixic acid; that from the Kanagawa Prefecture to cefazolin, cefotaxime, aztreonam, ciprofloxacin, and levofloxacin and that from Chiba Prefecture to chloramphenicol and imipenem. Multidrug-resistant bacteria were detected in 18 dogs from both regions; β-lactamase genes (blaTEM, blaDHA-1, blaCTX-M-9 group CTX-M-14), quinolone-resistance protein genes (qnrB and qnrS), and mutations in quinolone-resistance-determining regions (gyrA and parC) were detected. These results could partially represent the AMR data in shelter dogs in the Kanto Region of Japan. Nature Publishing Group UK 2022-01-14 /pmc/articles/PMC8760262/ /pubmed/35031646 http://dx.doi.org/10.1038/s41598-021-04435-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Hata, Akihisa Fujitani, Noboru Ono, Fumiko Yoshikawa, Yasuhiro Surveillance of antimicrobial-resistant Escherichia coli in Sheltered dogs in the Kanto Region of Japan |
title | Surveillance of antimicrobial-resistant Escherichia coli in Sheltered dogs in the Kanto Region of Japan |
title_full | Surveillance of antimicrobial-resistant Escherichia coli in Sheltered dogs in the Kanto Region of Japan |
title_fullStr | Surveillance of antimicrobial-resistant Escherichia coli in Sheltered dogs in the Kanto Region of Japan |
title_full_unstemmed | Surveillance of antimicrobial-resistant Escherichia coli in Sheltered dogs in the Kanto Region of Japan |
title_short | Surveillance of antimicrobial-resistant Escherichia coli in Sheltered dogs in the Kanto Region of Japan |
title_sort | surveillance of antimicrobial-resistant escherichia coli in sheltered dogs in the kanto region of japan |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760262/ https://www.ncbi.nlm.nih.gov/pubmed/35031646 http://dx.doi.org/10.1038/s41598-021-04435-w |
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