Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice

Lung emphysema and chronic bronchitis are the two most common causes of chronic obstructive pulmonary disease. Excess macrophage elastase MMP-12, which is predominantly secreted from alveolar macrophages, is known to mediate the development of lung injury and emphysema. Here, we discovered the endol...

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Detalles Bibliográficos
Autores principales: Spix, Barbara, Butz, Elisabeth S., Chen, Cheng-Chang, Rosato, Anna Scotto, Tang, Rachel, Jeridi, Aicha, Kudrina, Veronika, Plesch, Eva, Wartenberg, Philipp, Arlt, Elisabeth, Briukhovetska, Daria, Ansari, Meshal, Günsel, Gizem Günes, Conlon, Thomas M., Wyatt, Amanda, Wetzel, Sandra, Teupser, Daniel, Holdt, Lesca M., Ectors, Fabien, Boekhoff, Ingrid, Boehm, Ulrich, García-Añoveros, Jaime, Saftig, Paul, Giera, Martin, Kobold, Sebastian, Schiller, Herbert B., Zierler, Susanna, Gudermann, Thomas, Wahl-Schott, Christian, Bracher, Franz, Yildirim, Ali Önder, Biel, Martin, Grimm, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760276/
https://www.ncbi.nlm.nih.gov/pubmed/35031603
http://dx.doi.org/10.1038/s41467-021-27860-x

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