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Structure and function of a family of tick-derived complement inhibitors targeting properdin

Activation of the serum-resident complement system begins a cascade that leads to activation of membrane-resident complement receptors on immune cells, thus coordinating serum and cellular immune responses. Whilst many molecules act to control inappropriate activation, Properdin is the only known po...

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Detalles Bibliográficos
Autores principales:	Braunger, Katharina, Ahn, Jiyoon, Jore, Matthijs M., Johnson, Steven, Tang, Terence T. L., Pedersen, Dennis V., Andersen, Gregers R., Lea, Susan M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760278/ https://www.ncbi.nlm.nih.gov/pubmed/35031611 http://dx.doi.org/10.1038/s41467-021-27920-2

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