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Risk factors for actinic cheilitis: A meta-analysis
Background. Actinic cheilitis (AC) is a potentially malignant disorder characterized by chronic lip inflammation, especially the lower lip, associated with accumulative exposure to solar radiation. The present study aimed to assess the possible risk factors related to AC. Methods. A search for studi...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tabriz University of Medical Sciences
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760378/ https://www.ncbi.nlm.nih.gov/pubmed/35070184 http://dx.doi.org/10.34172/joddd.2021.047 |
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author | Rodriguez-Archilla, Alberto Irfan-Bhatti, Amna |
author_facet | Rodriguez-Archilla, Alberto Irfan-Bhatti, Amna |
author_sort | Rodriguez-Archilla, Alberto |
collection | PubMed |
description | Background. Actinic cheilitis (AC) is a potentially malignant disorder characterized by chronic lip inflammation, especially the lower lip, associated with accumulative exposure to solar radiation. The present study aimed to assess the possible risk factors related to AC. Methods. A search for studies on AC risk factors was conducted in the following databases: PubMed (MEDLINE, Cochrane Library), Web of Science (WoS), and Google Scholar. For dichotomous outcomes, the estimates of the effects of intervention were expressed as odds ratios (ORs) using Mantel-Haenszel (M-H) method, and for continuous outcomes, the estimates of the effects of intervention were expressed as mean difference (MD) using the inverse variance (IV) method, both with 95% confidence intervals. Results. Twelve studies were considered in this meta-analysis. The factors from the highest to lowest risk of AC were having a low skin phototype (OR: 3.30), age >50 years (OR: 3.01), having high sun exposure, cumulative throughout life (OR: 2.13) as daily (OR: 2.00), being male (OR: 1.78), and being a drinker (OR: 1.56) or smoker (OR: 1.32). However, the use of sunscreen creams and caps/hats to protect against the sun were factors with no significant influence on the AC risk. Conclusion. Chronic sun exposure in subjects with low skin phototypes is the main risk factor for AC. |
format | Online Article Text |
id | pubmed-8760378 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Tabriz University of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-87603782022-01-21 Risk factors for actinic cheilitis: A meta-analysis Rodriguez-Archilla, Alberto Irfan-Bhatti, Amna J Dent Res Dent Clin Dent Prospects Meta Analysis Background. Actinic cheilitis (AC) is a potentially malignant disorder characterized by chronic lip inflammation, especially the lower lip, associated with accumulative exposure to solar radiation. The present study aimed to assess the possible risk factors related to AC. Methods. A search for studies on AC risk factors was conducted in the following databases: PubMed (MEDLINE, Cochrane Library), Web of Science (WoS), and Google Scholar. For dichotomous outcomes, the estimates of the effects of intervention were expressed as odds ratios (ORs) using Mantel-Haenszel (M-H) method, and for continuous outcomes, the estimates of the effects of intervention were expressed as mean difference (MD) using the inverse variance (IV) method, both with 95% confidence intervals. Results. Twelve studies were considered in this meta-analysis. The factors from the highest to lowest risk of AC were having a low skin phototype (OR: 3.30), age >50 years (OR: 3.01), having high sun exposure, cumulative throughout life (OR: 2.13) as daily (OR: 2.00), being male (OR: 1.78), and being a drinker (OR: 1.56) or smoker (OR: 1.32). However, the use of sunscreen creams and caps/hats to protect against the sun were factors with no significant influence on the AC risk. Conclusion. Chronic sun exposure in subjects with low skin phototypes is the main risk factor for AC. Tabriz University of Medical Sciences 2021 2021-12-05 /pmc/articles/PMC8760378/ /pubmed/35070184 http://dx.doi.org/10.34172/joddd.2021.047 Text en © 2021 The Author(s). https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Meta Analysis Rodriguez-Archilla, Alberto Irfan-Bhatti, Amna Risk factors for actinic cheilitis: A meta-analysis |
title | Risk factors for actinic cheilitis: A meta-analysis |
title_full | Risk factors for actinic cheilitis: A meta-analysis |
title_fullStr | Risk factors for actinic cheilitis: A meta-analysis |
title_full_unstemmed | Risk factors for actinic cheilitis: A meta-analysis |
title_short | Risk factors for actinic cheilitis: A meta-analysis |
title_sort | risk factors for actinic cheilitis: a meta-analysis |
topic | Meta Analysis |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760378/ https://www.ncbi.nlm.nih.gov/pubmed/35070184 http://dx.doi.org/10.34172/joddd.2021.047 |
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