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Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease

Progression of autosomal dominant polycystic kidney disease (ADPKD) is modified by metabolic defects and obesity. Indeed, reduced food intake slows cyst growth in preclinical rodent studies. Here, we demonstrate the feasibility of daily caloric restriction (DCR) and intermittent fasting (IMF) in a c...

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Detalles Bibliográficos
Autores principales: Hopp, Katharina, Catenacci, Victoria A., Dwivedi, Nidhi, Kline, Timothy L., Wang, Wei, You, Zhiying, Nguyen, Dustin T., Bing, Kristen, Poudyal, Bhavya, Johnson, Ginger C., Jackman, Matthew R., Miller, Marsha, Steele, Cortney N., Serkova, Natalie J., MacLean, Paul S., Nemenoff, Raphael A., Gitomer, Berenice, Chonchol, Michel, Nowak, Kristen L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760407/
https://www.ncbi.nlm.nih.gov/pubmed/35059607
http://dx.doi.org/10.1016/j.isci.2021.103697