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Letter to the Editor: Epidemiology holds a key to the validation of toxicological models for elongate mineral particles
The authors reply to the comments of Drs. Gualtieri and di Giuseppe on the short communication by Wylie and Korchevskiy – Carcinogenicity of fibrous glaucophane: how to fill data gaps? (2021 Current Research in Toxicology Volume 2, pp. 202–203). The role of epidemiology in establishing the toxicity...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760428/ https://www.ncbi.nlm.nih.gov/pubmed/35059647 http://dx.doi.org/10.1016/j.crtox.2021.100062 |
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author | Wylie, Ann Korchevskiy, Andrey |
author_facet | Wylie, Ann Korchevskiy, Andrey |
author_sort | Wylie, Ann |
collection | PubMed |
description | The authors reply to the comments of Drs. Gualtieri and di Giuseppe on the short communication by Wylie and Korchevskiy – Carcinogenicity of fibrous glaucophane: how to fill data gaps? (2021 Current Research in Toxicology Volume 2, pp. 202–203). The role of epidemiology in establishing the toxicity of elongate mineral particles is emphasized. The validation of quantitative structure–activity relationship (QSAR) models by disease outcome is mentioned as one of the most important tools in advancing the new approaches in mineral particle toxicology. |
format | Online Article Text |
id | pubmed-8760428 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-87604282022-01-19 Letter to the Editor: Epidemiology holds a key to the validation of toxicological models for elongate mineral particles Wylie, Ann Korchevskiy, Andrey Curr Res Toxicol Article The authors reply to the comments of Drs. Gualtieri and di Giuseppe on the short communication by Wylie and Korchevskiy – Carcinogenicity of fibrous glaucophane: how to fill data gaps? (2021 Current Research in Toxicology Volume 2, pp. 202–203). The role of epidemiology in establishing the toxicity of elongate mineral particles is emphasized. The validation of quantitative structure–activity relationship (QSAR) models by disease outcome is mentioned as one of the most important tools in advancing the new approaches in mineral particle toxicology. Elsevier 2022-01-05 /pmc/articles/PMC8760428/ /pubmed/35059647 http://dx.doi.org/10.1016/j.crtox.2021.100062 Text en © 2022 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Wylie, Ann Korchevskiy, Andrey Letter to the Editor: Epidemiology holds a key to the validation of toxicological models for elongate mineral particles |
title | Letter to the Editor: Epidemiology holds a key to the validation of toxicological models for elongate mineral particles |
title_full | Letter to the Editor: Epidemiology holds a key to the validation of toxicological models for elongate mineral particles |
title_fullStr | Letter to the Editor: Epidemiology holds a key to the validation of toxicological models for elongate mineral particles |
title_full_unstemmed | Letter to the Editor: Epidemiology holds a key to the validation of toxicological models for elongate mineral particles |
title_short | Letter to the Editor: Epidemiology holds a key to the validation of toxicological models for elongate mineral particles |
title_sort | letter to the editor: epidemiology holds a key to the validation of toxicological models for elongate mineral particles |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760428/ https://www.ncbi.nlm.nih.gov/pubmed/35059647 http://dx.doi.org/10.1016/j.crtox.2021.100062 |
work_keys_str_mv | AT wylieann lettertotheeditorepidemiologyholdsakeytothevalidationoftoxicologicalmodelsforelongatemineralparticles AT korchevskiyandrey lettertotheeditorepidemiologyholdsakeytothevalidationoftoxicologicalmodelsforelongatemineralparticles |