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Glucose fluxes in glycolytic and oxidative pathways detected in vivo by deuterium magnetic resonance spectroscopy reflect proliferation in mouse glioblastoma

OBJECTIVES: Glioblastoma multiforme (GBM), the most aggressive glial brain tumors, can metabolize glucose through glycolysis and mitochondrial oxidation pathways. While specific dependencies on those pathways are increasingly associated with treatment response, detecting such GBM subtypes in vivo re...

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Detalles Bibliográficos
Autores principales: Simões, Rui V., Henriques, Rafael N., Cardoso, Beatriz M., Fernandes, Francisca F., Carvalho, Tânia, Shemesh, Noam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760481/
https://www.ncbi.nlm.nih.gov/pubmed/35026626
http://dx.doi.org/10.1016/j.nicl.2021.102932