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Glucose fluxes in glycolytic and oxidative pathways detected in vivo by deuterium magnetic resonance spectroscopy reflect proliferation in mouse glioblastoma
OBJECTIVES: Glioblastoma multiforme (GBM), the most aggressive glial brain tumors, can metabolize glucose through glycolysis and mitochondrial oxidation pathways. While specific dependencies on those pathways are increasingly associated with treatment response, detecting such GBM subtypes in vivo re...
Autores principales: | Simões, Rui V., Henriques, Rafael N., Cardoso, Beatriz M., Fernandes, Francisca F., Carvalho, Tânia, Shemesh, Noam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760481/ https://www.ncbi.nlm.nih.gov/pubmed/35026626 http://dx.doi.org/10.1016/j.nicl.2021.102932 |
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