Quantitative analysis of the formation of nucleoprotein complexes between HIV-1 Gag protein and genomic RNA using transmission electron microscopy

In HIV, the polyprotein precursor Gag orchestrates the formation of the viral capsid. In the current view of this viral assembly, Gag forms low-order oligomers that bind to the viral genomic RNA triggering the formation of high-ordered ribonucleoprotein complexes. However, this assembly model was es...

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Detalles Bibliográficos
Autores principales: Durand, Stéphanie, Seigneuret, Florian, Burlaud-Gaillard, Julien, Lemoine, Roxane, Tassi, Marc-Florent, Moreau, Alain, Mougel, Marylène, Roingeard, Philippe, Tauber, Clovis, de Rocquigny, Hugues
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760521/
https://www.ncbi.nlm.nih.gov/pubmed/34929171
http://dx.doi.org/10.1016/j.jbc.2021.101500

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