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MGcount: a total RNA-seq quantification tool to address multi-mapping and multi-overlapping alignments ambiguity in non-coding transcripts
BACKGROUND: Total-RNA sequencing (total-RNA-seq) allows the simultaneous study of both the coding and the non-coding transcriptome. Yet, computational pipelines have traditionally focused on particular biotypes, making assumptions that are not fullfilled by total-RNA-seq datasets. Transcripts from d...
Autores principales: | Hita, Andrea, Brocart, Gilles, Fernandez, Ana, Rehmsmeier, Marc, Alemany, Anna, Schvartzman, Sol |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760670/ https://www.ncbi.nlm.nih.gov/pubmed/35030988 http://dx.doi.org/10.1186/s12859-021-04544-3 |
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