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SHC4 promotes tumor proliferation and metastasis by activating STAT3 signaling in hepatocellular carcinoma

BACKGROUND: The Src homology and collagen 4 (SHC4) is an important intracellular adaptor protein that has been shown to play a pro-cancer role in melanoma and glioma. However, the biological function and detailed mechanisms of SHC4 in hepatocellular carcinoma progression are unclear. This study aime...

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Detalles Bibliográficos
Autores principales: Zhang, Xin, Zhang, Hongwei, Liao, Zhibin, Zhang, Jiacheng, Liang, Huifang, Wang, Weixing, Yu, Jia, Dong, Keshuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760801/
https://www.ncbi.nlm.nih.gov/pubmed/35033067
http://dx.doi.org/10.1186/s12935-022-02446-9