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Landscape of driver gene events, biomarkers, and druggable targets identified by whole-genome sequencing of glioblastomas

BACKGROUND: The survival of glioblastoma patients is poor. Median survival after diagnosis is 15 months, despite treatment involving surgical resection, radiotherapy, and/or temozolomide chemotherapy. Identification of novel targets and stratification strategies of glioblastoma patients to improve p...

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Detalles Bibliográficos
Autores principales:	van de Geer, Wesley S, Hoogstrate, Youri, Draaisma, Kaspar, Robe, Pierre A, Bins, Sander, Mathijssen, Ron H J, French, Pim, van de Werken, Harmen J G, de Vos, Filip Y F
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	Basic and Translational Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760899/ https://www.ncbi.nlm.nih.gov/pubmed/35047820 http://dx.doi.org/10.1093/noajnl/vdab177

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