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La transdisciplinariedad en el abordaje de la amiloidosis

The increasing complexity in the approach to diseases challenges the development of a new paradigm of care that crosses disciplinary limits, where professionals from different disciplines approach a problem applying their expertise, respecting the knowledge of the other and contributing to the globa...

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Autores principales: Alfonsín, Amalia Ernestina, Nucifora, Elsa Mercedes, Aguirre, María Adela, Posadas Martínez, María Lourdes, Valeo Chulvi, Melina Paula, Kohan, Dana, Escada, Sofía Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Universidad Nacional de Córdoba 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760903/
https://www.ncbi.nlm.nih.gov/pubmed/34617706
http://dx.doi.org/10.3105310.31053/1853.0605.v78.n3.32341
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author Alfonsín, Amalia Ernestina
Nucifora, Elsa Mercedes
Aguirre, María Adela
Posadas Martínez, María Lourdes
Valeo Chulvi, Melina Paula
Kohan, Dana
Escada, Sofía Stephanie
author_facet Alfonsín, Amalia Ernestina
Nucifora, Elsa Mercedes
Aguirre, María Adela
Posadas Martínez, María Lourdes
Valeo Chulvi, Melina Paula
Kohan, Dana
Escada, Sofía Stephanie
author_sort Alfonsín, Amalia Ernestina
collection PubMed
description The increasing complexity in the approach to diseases challenges the development of a new paradigm of care that crosses disciplinary limits, where professionals from different disciplines approach a problem applying their expertise, respecting the knowledge of the other and contributing to the global view of the problem. Amyloidoses are rare diseases. The diagnosis is based on the biopsy of those organs in which amyloid infiltration is suspected. There is an increased risk of bleeding associated with these procedures. Therefore, the availability of obtaining samples from certain sites with less invasive accesses, such as the minor salivary glands (GSM), represent an alternative. Objectives: Describe the experiences of GSM biopsies as a diagnostic tool in the detection of amyloidosis and its intra and postoperative complications. - Estimate the diagnostic performance. The design is a cross-sectional cohort. All patients with a suspected diagnosis of amyloidosis were consecutively included, between August 2018-September 2020. Results: 23 biopsies were performed with minimally invasive procedures. 60.86% were male and the average age was 66 years. The prevalence of amyloidosis was 33%. The sensitivity was 55% and the specificity 100%. One patient had more bleeding than usual during the procedure and none had postoperative complications. Conclusions: GSM biopsy experiences were described as a diagnostic tool for amyloidosis, reporting a slight intraoperative complication and no postoperative complication. The test achieved a sensitivity of 55% and a specificity of 100%.
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spelling pubmed-87609032022-01-18 La transdisciplinariedad en el abordaje de la amiloidosis Alfonsín, Amalia Ernestina Nucifora, Elsa Mercedes Aguirre, María Adela Posadas Martínez, María Lourdes Valeo Chulvi, Melina Paula Kohan, Dana Escada, Sofía Stephanie Rev Fac Cien Med Univ Nac Cordoba Originales Breves The increasing complexity in the approach to diseases challenges the development of a new paradigm of care that crosses disciplinary limits, where professionals from different disciplines approach a problem applying their expertise, respecting the knowledge of the other and contributing to the global view of the problem. Amyloidoses are rare diseases. The diagnosis is based on the biopsy of those organs in which amyloid infiltration is suspected. There is an increased risk of bleeding associated with these procedures. Therefore, the availability of obtaining samples from certain sites with less invasive accesses, such as the minor salivary glands (GSM), represent an alternative. Objectives: Describe the experiences of GSM biopsies as a diagnostic tool in the detection of amyloidosis and its intra and postoperative complications. - Estimate the diagnostic performance. The design is a cross-sectional cohort. All patients with a suspected diagnosis of amyloidosis were consecutively included, between August 2018-September 2020. Results: 23 biopsies were performed with minimally invasive procedures. 60.86% were male and the average age was 66 years. The prevalence of amyloidosis was 33%. The sensitivity was 55% and the specificity 100%. One patient had more bleeding than usual during the procedure and none had postoperative complications. Conclusions: GSM biopsy experiences were described as a diagnostic tool for amyloidosis, reporting a slight intraoperative complication and no postoperative complication. The test achieved a sensitivity of 55% and a specificity of 100%. Universidad Nacional de Córdoba 2021-08-23 /pmc/articles/PMC8760903/ /pubmed/34617706 http://dx.doi.org/10.3105310.31053/1853.0605.v78.n3.32341 Text en https://creativecommons.org/licenses/by-nc/4.0/Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial 4.0.
spellingShingle Originales Breves
Alfonsín, Amalia Ernestina
Nucifora, Elsa Mercedes
Aguirre, María Adela
Posadas Martínez, María Lourdes
Valeo Chulvi, Melina Paula
Kohan, Dana
Escada, Sofía Stephanie
La transdisciplinariedad en el abordaje de la amiloidosis
title La transdisciplinariedad en el abordaje de la amiloidosis
title_full La transdisciplinariedad en el abordaje de la amiloidosis
title_fullStr La transdisciplinariedad en el abordaje de la amiloidosis
title_full_unstemmed La transdisciplinariedad en el abordaje de la amiloidosis
title_short La transdisciplinariedad en el abordaje de la amiloidosis
title_sort la transdisciplinariedad en el abordaje de la amiloidosis
topic Originales Breves
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760903/
https://www.ncbi.nlm.nih.gov/pubmed/34617706
http://dx.doi.org/10.3105310.31053/1853.0605.v78.n3.32341
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