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Exploring a Novel Fasudil-Phospholipid Complex Formulated as Liposomal Thermosensitive in situ Gel for Glaucoma

PURPOSE: Fasudil hydrochloride (Fas), a rho-associated protein kinase inhibitor, proved to be promising for glaucoma management owing to its IOP lowering and antioxidant effects. However, its highly hydrophilic nature limits ocular permeation and bioavailability. Hence, the study objective was the d...

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Detalles Bibliográficos
Autores principales: Khallaf, Aya M, El-Moslemany, Riham M, Ahmed, Mahmoud F, Morsi, Mahmoud H, Khalafallah, Nawal M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8760977/
https://www.ncbi.nlm.nih.gov/pubmed/35046652
http://dx.doi.org/10.2147/IJN.S342975

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