Cargando…

RNF6 Targeted by miR-26a-5p Protects Pancreatic β-Cell Function Against Type 2 Diabetes

BACKGROUND: Type 2 diabetes (T2D) is characterized by progressive β-cell dysfunction. Regulatory microRNAs (miRNAs) may be associated with this. METHODS: Serum miR-26a-5p and RNF6 levels were detected in T2D patients and healthy volunteers via qRT-PCR. Subsequently, the role of specific dysregulated...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yang, Fan, Zhao, Shengxun, Zhang, Xuyan, Ding, Sheng, Xu, Yancheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761081/ https://www.ncbi.nlm.nih.gov/pubmed/35046680 http://dx.doi.org/10.2147/DMSO.S335088

Ejemplares similares

miR-26a enhances autophagy to protect against ethanol-induced acute liver injury
por: Han, Weidong, et al.
Publicado: (2015)

miR-433 protects pancreatic β cell growth in high-glucose conditions
por: Wang, Min
Publicado: (2017)

Bioinformatic Identification of miR-622 Key Target Genes and Experimental Validation of the miR-622-RNF8 Axis in Breast Cancer
por: Liu, Chuanyang, et al.
Publicado: (2019)

Ginsenoside Rg3 protects mouse leydig cells against triptolide by downregulation of miR-26a
por: Liang, Haiyan, et al.
Publicado: (2019)

CircRNF111 Protects Against Insulin Resistance and Lipid Deposition via Regulating miR-143-3p/IGF2R Axis in Metabolic Syndrome
por: Lin, Xihua, et al.
Publicado: (2021)

CircRNF13 Promotes the Malignant Progression of Pancreatic Cancer through Targeting miR-139-5p/IGF1R Axis
por: Liu, Xinyuan, et al.
Publicado: (2021)

circRNF20 aggravates the malignancy of retinoblastoma depending on the regulation of miR-132-3p/PAX6 axis
por: An, Dexiang, et al.
Publicado: (2022)

The Roles of miR-26, miR-29, and miR-203 in the Silencing of the Epigenetic Machinery during Melanocyte Transformation
por: Gasque Schoof, Cláudia Regina, et al.
Publicado: (2015)

Deficiency of a novel lncRNA-HRAT protects against myocardial ischemia reperfusion injury by targeting miR-370-3p/RNF41 pathway
por: Zheng, Xinbin, et al.
Publicado: (2022)

Circulating miR-20a and miR-26a as Biomarkers in Prostate Cancer
por: Torbati, Peyman Mohammadi, et al.
Publicado: (2019)

Circulating miR-26a-1, miR-146a and miR-199a-1 are potential candidate biomarkers for acute myocardial infarction
por: Xue, Sheng, et al.
Publicado: (2019)

MiR-21, miR-34a, miR-198 and miR-217 as diagnostic and prognostic biomarkers for chronic pancreatitis and pancreatic ductal adenocarcinoma
por: Vychytilova-Faltejskova, Petra, et al.
Publicado: (2015)

MiR-26a/miR-26b represses tongue squamous cell carcinoma progression by targeting PAK1
por: Wei, Zhenxing, et al.
Publicado: (2020)

miR-125a, miR-139 and miR-324 contribute to Urocortin protection against myocardial ischemia-reperfusion injury
por: Díaz, Ignacio, et al.
Publicado: (2017)

miR-494 protects pancreatic β-cell function by targeting PTEN in gestational diabetes mellitus
por: He, Yanfang, et al.
Publicado: (2017)

MiR-21-5p protects against ischemic stroke by targeting IL-6R
por: Zhan, Lan, et al.
Publicado: (2023)

Dysregulation of MiR-144-5p/RNF187 Axis Contributes To the Progression of Colorectal Cancer
por: Gao, Zhuo, et al.
Publicado: (2022)

Identification of miR-10b, miR-26a, miR-146a and miR-153 as potential triple-negative breast cancer biomarkers
por: Fkih M’hamed, Insaf, et al.
Publicado: (2015)

MiR-29a and MiR-140 Protect Chondrocytes against the Anti-Proliferation and Cell Matrix Signaling Changes by IL-1β
por: Li, Xianghui, et al.
Publicado: (2016)

Reduced miR-26a and miR-26b expression contributes to the pathogenesis of osteoarthritis via the promotion of p65 translocation
por: Yin, Xuefeng, et al.
Publicado: (2017)

Tumor-suppressive miR-26a and miR-26b inhibit cell aggressiveness by regulating FUT4 in colorectal cancer
por: Li, Yang, et al.
Publicado: (2017)

Expression Profiling and Functional Characterization of miR-26a and miR-130a in Regulating Zhongwei Goat Hair Development via the TGF-β/SMAD Pathway
por: Ding, Yangyang, et al.
Publicado: (2020)

Elevated Serum miR-7, miR-9, miR-122, and miR-141 Are Noninvasive Biomarkers of Acute Pancreatitis
por: Lu, Pan, et al.
Publicado: (2017)

MicroRNAs miR-26a, miR-26b, and miR-29b accelerate osteogenic differentiation of unrestricted somatic stem cells from human cord blood
por: Trompeter, Hans-Ingo, et al.
Publicado: (2013)

Clinical impact of circulating miR-26a, miR-191, and miR-208b in plasma of patients with acute myocardial infarction
por: Li, Chencheng, et al.
Publicado: (2015)

lncRNA SNHG6 regulates EZH2 expression by sponging miR-26a/b and miR-214 in colorectal cancer
por: Xu, Mu, et al.
Publicado: (2019)

Association study of relationships of polymorphisms in the miR-21, miR-26b, miR-221/222 and miR-126 genes with cervical intraepithelial neoplasia and cervical cancer
por: Yang, Jia, et al.
Publicado: (2021)

miR-26a and miR-384-5p are required for LTP maintenance and spine enlargement
por: Gu, Qin-Hua, et al.
Publicado: (2015)

The coordinated roles of miR-26a and miR-30c in regulating TGFβ1-induced epithelial-to-mesenchymal transition in diabetic nephropathy
por: Zheng, Zongji, et al.
Publicado: (2016)

The microRNAs miR-204 and miR-211 maintain joint homeostasis and protect against osteoarthritis progression
por: Huang, Jian, et al.
Publicado: (2019)

Conservation and diversification of the miR166 family in soybean and potential roles of newly identified miR166s
por: Li, Xuyan, et al.
Publicado: (2017)

MiR-26a and miR-144 inhibit proliferation and metastasis of esophageal squamous cell cancer by inhibiting cyclooxygenase-2
por: Shao, Ying, et al.
Publicado: (2016)

Plasma exosome miR-196a and miR-1246 are potential indicators of localized pancreatic cancer
por: Xu, Yi-Fan, et al.
Publicado: (2017)

miR-18a counteracts AKT and ERK activation to inhibit the proliferation of pancreatic progenitor cells
por: Li, Xuyan, et al.
Publicado: (2017)

Serum miR-26a as a diagnostic and prognostic biomarker in cholangiocarcinoma
por: Wang, Li-Juan, et al.
Publicado: (2015)

Brain Derived Neurotrophic Factor (BDNF) Expression Is Regulated by MicroRNAs miR-26a and miR-26b Allele-Specific Binding
por: Caputo, Viviana, et al.
Publicado: (2011)

Dysregulation of miR-15a and miR-214 in human pancreatic cancer
por: Zhang, Xing J, et al.
Publicado: (2010)

Natalizumab Therapy Modulates miR-155, miR-26a and Proinflammatory Cytokine Expression in MS Patients
por: Mameli, Giuseppe, et al.
Publicado: (2016)

miR-214 Protects Against Uric Acid-Induced Endothelial Cell Apoptosis
por: Yang, Bingyu, et al.
Publicado: (2020)

Decreased Expression of miR-21, miR-26a, miR-29a, and miR-142-3p in CD4(+) T Cells and Peripheral Blood from Tuberculosis Patients
por: Kleinsteuber, Katja, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_pp2hrg43smv3l58477prfrlkph