Persistently elevated complement alternative pathway biomarkers in COVID-19 correlate with hypoxemia and predict in-hospital mortality

Mechanisms underlying the SARS-CoV-2-triggered hyperacute thrombo-inflammatory response that causes multi-organ damage in coronavirus disease 2019 (COVID-19) are poorly understood. Several lines of evidence implicate overactivation of complement. To delineate the involvement of complement in COVID-1...

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Detalles Bibliográficos
Autores principales: Leatherdale, Alexander, Stukas, Sophie, Lei, Victor, West, Henry E., Campbell, Christopher J., Hoiland, Ryan L., Cooper, Jennifer, Wellington, Cheryl L., Sekhon, Mypinder S., Pryzdial, Edward L. G., Conway, Edward M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761108/
https://www.ncbi.nlm.nih.gov/pubmed/35034207
http://dx.doi.org/10.1007/s00430-021-00725-2

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