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Ins and outs of AlphaFold2 transmembrane protein structure predictions
Transmembrane (TM) proteins are major drug targets, but their structure determination, a prerequisite for rational drug design, remains challenging. Recently, the DeepMind’s AlphaFold2 machine learning method greatly expanded the structural coverage of sequences with high accuracy. Since the employe...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761152/ https://www.ncbi.nlm.nih.gov/pubmed/35034173 http://dx.doi.org/10.1007/s00018-021-04112-1 |