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Advanced Paternal Age and Sperm DNA Fragmentation: A Systematic Review

PURPOSE: Male ageing is often associated with defective sperm DNA remodeling mechanisms that result in poorly packaged chromatin and a decreased ability to repair DNA strand breaks. However, the impact of advanced paternal age on DNA fragmentation remains inconclusive. The aim of the present systema...

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Detalles Bibliográficos
Autores principales: Gonzalez, Daniel C., Ory, Jesse, Blachman-Braun, Ruben, Nackeeran, Sirpi, Best, Jordan C., Ramasamy, Ranjith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Sexual Medicine and Andrology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761235/
https://www.ncbi.nlm.nih.gov/pubmed/33987998
http://dx.doi.org/10.5534/wjmh.200195