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Transurethral Microwave Thermotherapy for Benign Prostatic Hyperplasia: An Updated Cochrane Review

PURPOSE: To assess the effects of transurethral microwave thermotherapy (TUMT) for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: We performed a comprehensive search using multiple databases up to May 2021, with no language or pub...

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Autores principales: Franco, Juan Victor Ariel, Garegnani, Luis, Escobar Liquitay, Camila Micaela, Borofsky, Michael, Dahm, Philipp
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Sexual Medicine and Andrology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761240/
https://www.ncbi.nlm.nih.gov/pubmed/34448377
http://dx.doi.org/10.5534/wjmh.210115
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author Franco, Juan Victor Ariel
Garegnani, Luis
Escobar Liquitay, Camila Micaela
Borofsky, Michael
Dahm, Philipp
author_facet Franco, Juan Victor Ariel
Garegnani, Luis
Escobar Liquitay, Camila Micaela
Borofsky, Michael
Dahm, Philipp
author_sort Franco, Juan Victor Ariel
collection PubMed
description PURPOSE: To assess the effects of transurethral microwave thermotherapy (TUMT) for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: We performed a comprehensive search using multiple databases up to May 2021, with no language or publication status restrictions. We included parallel-group randomized controlled trials of participants with BPH who underwent TUMT. We used standard Cochrane methods, including a GRADE assessment of the certainty of the evidence (CoE). RESULTS: In this update of a previous Cochrane review, we included 16 trials with 1,919 participants. TUMT probably results in little to no difference in urologic symptom scores at short-term follow-up compared to transurethral resection of the prostate (TURP). There is likely to be little to no difference in the quality of life. TUMT likely results in fewer major adverse events. TUMT, however, probably results in a large increase in the need for retreatment. There may be little to no difference in erectile function between these interventions. However, TUMT may result in fewer cases of ejaculatory dysfunction compared to TURP. The overall CoE was moderate to low. CONCLUSIONS: TUMT provides a similar reduction in urinary symptoms compared to TURP, with fewer major adverse events and fewer cases of ejaculatory dysfunction at short-term follow-up. However, TUMT probably results in a large increase in retreatment rates. Study limitations and imprecision reduced the confidence we can place in these results.
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spelling pubmed-87612402022-01-25 Transurethral Microwave Thermotherapy for Benign Prostatic Hyperplasia: An Updated Cochrane Review Franco, Juan Victor Ariel Garegnani, Luis Escobar Liquitay, Camila Micaela Borofsky, Michael Dahm, Philipp World J Mens Health Original Article PURPOSE: To assess the effects of transurethral microwave thermotherapy (TUMT) for the treatment of lower urinary tract symptoms in men with benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: We performed a comprehensive search using multiple databases up to May 2021, with no language or publication status restrictions. We included parallel-group randomized controlled trials of participants with BPH who underwent TUMT. We used standard Cochrane methods, including a GRADE assessment of the certainty of the evidence (CoE). RESULTS: In this update of a previous Cochrane review, we included 16 trials with 1,919 participants. TUMT probably results in little to no difference in urologic symptom scores at short-term follow-up compared to transurethral resection of the prostate (TURP). There is likely to be little to no difference in the quality of life. TUMT likely results in fewer major adverse events. TUMT, however, probably results in a large increase in the need for retreatment. There may be little to no difference in erectile function between these interventions. However, TUMT may result in fewer cases of ejaculatory dysfunction compared to TURP. The overall CoE was moderate to low. CONCLUSIONS: TUMT provides a similar reduction in urinary symptoms compared to TURP, with fewer major adverse events and fewer cases of ejaculatory dysfunction at short-term follow-up. However, TUMT probably results in a large increase in retreatment rates. Study limitations and imprecision reduced the confidence we can place in these results. Korean Society for Sexual Medicine and Andrology 2022-01 2021-08-04 /pmc/articles/PMC8761240/ /pubmed/34448377 http://dx.doi.org/10.5534/wjmh.210115 Text en Copyright © 2022 Korean Society for Sexual Medicine and Andrology https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0 (https://creativecommons.org/licenses/by-nc/4.0/) ) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Franco, Juan Victor Ariel
Garegnani, Luis
Escobar Liquitay, Camila Micaela
Borofsky, Michael
Dahm, Philipp
Transurethral Microwave Thermotherapy for Benign Prostatic Hyperplasia: An Updated Cochrane Review
title Transurethral Microwave Thermotherapy for Benign Prostatic Hyperplasia: An Updated Cochrane Review
title_full Transurethral Microwave Thermotherapy for Benign Prostatic Hyperplasia: An Updated Cochrane Review
title_fullStr Transurethral Microwave Thermotherapy for Benign Prostatic Hyperplasia: An Updated Cochrane Review
title_full_unstemmed Transurethral Microwave Thermotherapy for Benign Prostatic Hyperplasia: An Updated Cochrane Review
title_short Transurethral Microwave Thermotherapy for Benign Prostatic Hyperplasia: An Updated Cochrane Review
title_sort transurethral microwave thermotherapy for benign prostatic hyperplasia: an updated cochrane review
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761240/
https://www.ncbi.nlm.nih.gov/pubmed/34448377
http://dx.doi.org/10.5534/wjmh.210115
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