Malnutrition on admission increases the in‐hospital mortality and length of stay in elder adults with acute ischemic stroke

PURPOSE: Malnutrition, as determined by the Controlling Nutritional Status (CONUT), has an effect on the 3‐month and long‐term prognosis of stroke patients. The association between malnutrition and in‐hospital mortality has not been well established. We aimed to investigate the relationship between...

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Autores principales: Hao, Ruixiao, Qi, Xuemei, Xia, Xiaoshuang, Wang, Lin, Li, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761426/
https://www.ncbi.nlm.nih.gov/pubmed/34877710
http://dx.doi.org/10.1002/jcla.24132
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author Hao, Ruixiao
Qi, Xuemei
Xia, Xiaoshuang
Wang, Lin
Li, Xin
author_facet Hao, Ruixiao
Qi, Xuemei
Xia, Xiaoshuang
Wang, Lin
Li, Xin
author_sort Hao, Ruixiao
collection PubMed
description PURPOSE: Malnutrition, as determined by the Controlling Nutritional Status (CONUT), has an effect on the 3‐month and long‐term prognosis of stroke patients. The association between malnutrition and in‐hospital mortality has not been well established. We aimed to investigate the relationship between the CONUT score on admission and in‐hospital mortality and length of stay (LOS) in elderly patients with acute ischemic stroke (AIS). METHODS: This study analyzed controls and patients with AIS. Malnutrition was determined using the CONUT score. A CONUT score of 5–12 was defined as undernutrition status. Based on the CONUT scores, the patients were divided into the low CONUT (0–4) and high CONUT (5–12) groups. RESULTS: In total, 1079 participants were recruited, comprising 288 controls and 791 AIS patients. Among the 791 patients, 64 (8.1%) had malnutrition and 63 (7.9%) had an in‐hospital death. Compared to the controls, the AIS patients presented higher CONUT scores, higher proportion of in‐hospital mortality (8.0%), and longer length of stay. Malnutrition was independently associated with in‐hospital mortality in the AIS patients (adjusted odds ratio: 3.77, 95% confidence interval [CI]: 1.55–9.15; p = 0.003). The general linear models showed an association between the CONUT score and LOS (β = 0.574, 95% CI: 0.208–0.934; p = 0.002). Furthermore, the effect of the interaction between infection and nutrition status on in‐hospital mortality showed borderline statistical significance (p = 0.06). CONCLUSIONS: Malnutrition estimated by the CONUT score on admission can be a predictor of in‐hospital mortality and increased LOS in elderly AIS patients.
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spelling pubmed-87614262022-01-20 Malnutrition on admission increases the in‐hospital mortality and length of stay in elder adults with acute ischemic stroke Hao, Ruixiao Qi, Xuemei Xia, Xiaoshuang Wang, Lin Li, Xin J Clin Lab Anal Research Articles PURPOSE: Malnutrition, as determined by the Controlling Nutritional Status (CONUT), has an effect on the 3‐month and long‐term prognosis of stroke patients. The association between malnutrition and in‐hospital mortality has not been well established. We aimed to investigate the relationship between the CONUT score on admission and in‐hospital mortality and length of stay (LOS) in elderly patients with acute ischemic stroke (AIS). METHODS: This study analyzed controls and patients with AIS. Malnutrition was determined using the CONUT score. A CONUT score of 5–12 was defined as undernutrition status. Based on the CONUT scores, the patients were divided into the low CONUT (0–4) and high CONUT (5–12) groups. RESULTS: In total, 1079 participants were recruited, comprising 288 controls and 791 AIS patients. Among the 791 patients, 64 (8.1%) had malnutrition and 63 (7.9%) had an in‐hospital death. Compared to the controls, the AIS patients presented higher CONUT scores, higher proportion of in‐hospital mortality (8.0%), and longer length of stay. Malnutrition was independently associated with in‐hospital mortality in the AIS patients (adjusted odds ratio: 3.77, 95% confidence interval [CI]: 1.55–9.15; p = 0.003). The general linear models showed an association between the CONUT score and LOS (β = 0.574, 95% CI: 0.208–0.934; p = 0.002). Furthermore, the effect of the interaction between infection and nutrition status on in‐hospital mortality showed borderline statistical significance (p = 0.06). CONCLUSIONS: Malnutrition estimated by the CONUT score on admission can be a predictor of in‐hospital mortality and increased LOS in elderly AIS patients. John Wiley and Sons Inc. 2021-12-08 /pmc/articles/PMC8761426/ /pubmed/34877710 http://dx.doi.org/10.1002/jcla.24132 Text en © 2021 The Authors. Journal of Clinical Laboratory Analysis published by Wiley Periodicals LLC. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Research Articles
Hao, Ruixiao
Qi, Xuemei
Xia, Xiaoshuang
Wang, Lin
Li, Xin
Malnutrition on admission increases the in‐hospital mortality and length of stay in elder adults with acute ischemic stroke
title Malnutrition on admission increases the in‐hospital mortality and length of stay in elder adults with acute ischemic stroke
title_full Malnutrition on admission increases the in‐hospital mortality and length of stay in elder adults with acute ischemic stroke
title_fullStr Malnutrition on admission increases the in‐hospital mortality and length of stay in elder adults with acute ischemic stroke
title_full_unstemmed Malnutrition on admission increases the in‐hospital mortality and length of stay in elder adults with acute ischemic stroke
title_short Malnutrition on admission increases the in‐hospital mortality and length of stay in elder adults with acute ischemic stroke
title_sort malnutrition on admission increases the in‐hospital mortality and length of stay in elder adults with acute ischemic stroke
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761426/
https://www.ncbi.nlm.nih.gov/pubmed/34877710
http://dx.doi.org/10.1002/jcla.24132
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