Late onset of type 2 diabetes is associated with mitochondrial tRNA(Trp) A5514G and tRNA(Ser(AGY)) C12237T mutations

BACKGROUND: Mitochondrial dysfunctions caused by mitochondrial DNA (mtDNA) pathogenic mutations play putative roles in type 2 diabetes mellitus (T2DM) progression. But the underlying mechanism remains poorly understood. METHODS: A large Chinese family with maternally inherited diabetes and deafness...

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Detalles Bibliográficos
Autores principales: Yang, Liuchun, Guo, Qinxian, Leng, Jianhang, Wang, Keyi, Ding, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761459/
https://www.ncbi.nlm.nih.gov/pubmed/34811812
http://dx.doi.org/10.1002/jcla.24102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761459/
https://www.ncbi.nlm.nih.gov/pubmed/34811812
http://dx.doi.org/10.1002/jcla.24102

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