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Late onset of type 2 diabetes is associated with mitochondrial tRNA(Trp) A5514G and tRNA(Ser(AGY)) C12237T mutations
BACKGROUND: Mitochondrial dysfunctions caused by mitochondrial DNA (mtDNA) pathogenic mutations play putative roles in type 2 diabetes mellitus (T2DM) progression. But the underlying mechanism remains poorly understood. METHODS: A large Chinese family with maternally inherited diabetes and deafness...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761459/ https://www.ncbi.nlm.nih.gov/pubmed/34811812 http://dx.doi.org/10.1002/jcla.24102 |