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Coinfección de tuberculosis y COVID-19 asociado a tromboembolismo pulmonar: presentación de un caso

CONTEXT: Currently, infection by the SARS-CoV-2 virus predominantly generates a respiratory infection, which can lead to acute and late complications, as well as mild or severe sequelae. A complication that has been evidenced is the state of hypercoagulability, such as pulmonary thromboembolism (PE)...

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Autores principales: Theran León, Juan Sebastian, Esteban Badillo, Laura Yibeth, Villalobos, Mayra Alenadra, Dulcey, Luis Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier España, S.L.U. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761542/
http://dx.doi.org/10.1016/j.appr.2022.100129
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author Theran León, Juan Sebastian
Esteban Badillo, Laura Yibeth
Villalobos, Mayra Alenadra
Dulcey, Luis Andres
author_facet Theran León, Juan Sebastian
Esteban Badillo, Laura Yibeth
Villalobos, Mayra Alenadra
Dulcey, Luis Andres
author_sort Theran León, Juan Sebastian
collection PubMed
description CONTEXT: Currently, infection by the SARS-CoV-2 virus predominantly generates a respiratory infection, which can lead to acute and late complications, as well as mild or severe sequelae. A complication that has been evidenced is the state of hypercoagulability, such as pulmonary thromboembolism (PE) or deep vein thrombosis (DVT). CLINICAL CASE: We present the case of a patient with a recent history of COVID-19 infection who consulted for dyspnea and pain in the left hemithorax, complementary images were taken showing a large cavern at the right pulmonary base and an electrocardiogram suggestive of pulmonary thromboembolism, a CT scan was taken with protocol for PET that confirms it and smear microscopies that report positive for pulmonary tuberculosis coinfection. DISCUSSION AND CONCLUSIONS: The formation of prothrombotic phenomena by COVID-19 has become a frequent complication, however, the coinfection of tuberculosis and COVID-19 is rare, this is due to a process of amplification of the deregulated immune response called «cytokine storm», which activates latent and hidden infections, in addition the use of immunosuppressive drugs in COVID-19 can lead to an expression of tuberculosis. Tuberculosis infection should be suspected in an endemic environment together with persistence of symptoms after the resolution of the viral infection, symptomatic cases before the acute viral process or in cases of atypical radiographic findings; in these cases, HIV infection or infection should be ruled out. another bacterial coinfection.
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spelling pubmed-87615422022-01-18 Coinfección de tuberculosis y COVID-19 asociado a tromboembolismo pulmonar: presentación de un caso Theran León, Juan Sebastian Esteban Badillo, Laura Yibeth Villalobos, Mayra Alenadra Dulcey, Luis Andres Atención Primaria Práctica Caso Clínico CONTEXT: Currently, infection by the SARS-CoV-2 virus predominantly generates a respiratory infection, which can lead to acute and late complications, as well as mild or severe sequelae. A complication that has been evidenced is the state of hypercoagulability, such as pulmonary thromboembolism (PE) or deep vein thrombosis (DVT). CLINICAL CASE: We present the case of a patient with a recent history of COVID-19 infection who consulted for dyspnea and pain in the left hemithorax, complementary images were taken showing a large cavern at the right pulmonary base and an electrocardiogram suggestive of pulmonary thromboembolism, a CT scan was taken with protocol for PET that confirms it and smear microscopies that report positive for pulmonary tuberculosis coinfection. DISCUSSION AND CONCLUSIONS: The formation of prothrombotic phenomena by COVID-19 has become a frequent complication, however, the coinfection of tuberculosis and COVID-19 is rare, this is due to a process of amplification of the deregulated immune response called «cytokine storm», which activates latent and hidden infections, in addition the use of immunosuppressive drugs in COVID-19 can lead to an expression of tuberculosis. Tuberculosis infection should be suspected in an endemic environment together with persistence of symptoms after the resolution of the viral infection, symptomatic cases before the acute viral process or in cases of atypical radiographic findings; in these cases, HIV infection or infection should be ruled out. another bacterial coinfection. The Author(s). Published by Elsevier España, S.L.U. 2022 2022-01-17 /pmc/articles/PMC8761542/ http://dx.doi.org/10.1016/j.appr.2022.100129 Text en © 2022 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Caso Clínico
Theran León, Juan Sebastian
Esteban Badillo, Laura Yibeth
Villalobos, Mayra Alenadra
Dulcey, Luis Andres
Coinfección de tuberculosis y COVID-19 asociado a tromboembolismo pulmonar: presentación de un caso
title Coinfección de tuberculosis y COVID-19 asociado a tromboembolismo pulmonar: presentación de un caso
title_full Coinfección de tuberculosis y COVID-19 asociado a tromboembolismo pulmonar: presentación de un caso
title_fullStr Coinfección de tuberculosis y COVID-19 asociado a tromboembolismo pulmonar: presentación de un caso
title_full_unstemmed Coinfección de tuberculosis y COVID-19 asociado a tromboembolismo pulmonar: presentación de un caso
title_short Coinfección de tuberculosis y COVID-19 asociado a tromboembolismo pulmonar: presentación de un caso
title_sort coinfección de tuberculosis y covid-19 asociado a tromboembolismo pulmonar: presentación de un caso
topic Caso Clínico
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761542/
http://dx.doi.org/10.1016/j.appr.2022.100129
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