Oncogenic Gq/11 signaling acutely drives and chronically sustains metabolic reprogramming in uveal melanoma

Metabolic reprogramming has been shown to occur in uveal melanoma (UM), the most common intraocular tumor in adults. Mechanisms driving metabolic reprogramming in UM are poorly understood. Elucidation of these mechanisms could inform development of new therapeutic strategies for metastatic UM, which...

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Detalles Bibliográficos
Autores principales: Onken, Michael D., Noda, Sarah E., Kaltenbronn, Kevin M., Frankfater, Cheryl, Makepeace, Carol M., Fettig, Nikki, Piggott, Kisha D., Custer, Philip L., Ippolito, Joseph E., Blumer, Kendall J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761705/
https://www.ncbi.nlm.nih.gov/pubmed/34919964
http://dx.doi.org/10.1016/j.jbc.2021.101495

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