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The cGAS/STING Pathway: A Novel Target for Cancer Therapy

As a DNA receptor, cyclic GMP-AMP synthase (cGAS) plays a crucial role in the immune system by recognizing abnormal DNA in the cytoplasm and activating the stimulator of interferon genes (STING) signaling pathway. This signaling cascade reaction leads to an immune response produced by type I interfe...

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Detalles Bibliográficos
Autores principales:	Gan, Yu, Li, Xiaoying, Han, Shuangze, Liang, Qi, Ma, Xiaoqian, Rong, Pengfei, Wang, Wei, Li, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761794/ https://www.ncbi.nlm.nih.gov/pubmed/35046953 http://dx.doi.org/10.3389/fimmu.2021.795401

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