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Safety and Tolerability, Dose-Escalating, Double-Blind Trial of Oral Mannitol in Parkinson's Disease

Mannitol, a natural alcoholic-sugar, was recently suggested as a potential disease-modifying agent in Parkinson's disease. In animal models of the disease, mannitol interferes with the formation of α-synuclein fibrils, inhibits the formation of α-synuclein oligomers and leads to phenotypic reco...

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Detalles Bibliográficos
Autores principales: Linetsky, Eduard, Abd Elhadi, Suaad, Bauer, Max, Gallant, Akiva, Namnah, Montaser, Weiss, Sagit, Segal, Daniel, Sharon, Ronit, Arkadir, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761891/
https://www.ncbi.nlm.nih.gov/pubmed/35046880
http://dx.doi.org/10.3389/fneur.2021.716126

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