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Co-Expression of miR155 or LSD1 shRNA Increases the Anti-Tumor Functions of CD19 CAR-T Cells
Chimeric antigen receptor (CAR) T cells targeting CD19 antigen have produced remarkable clinical outcomes for cancer patients. However, identifying measures to enhance effector function remains one of the most challenging issues in CD19-targeted immunotherapy. Here, we report a novel approach in whi...
Autores principales: | Zhang, Jing, Zhu, Jingjing, Zheng, Genhui, Wang, Qianyu, Li, Xiaorui, Feng, Yaru, Shang, Fengqin, He, Siqi, Jiang, Qiyao, Shi, Bingjie, Wang, Dong, Cao, Zhiwei, Wang, Jianxun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8761951/ https://www.ncbi.nlm.nih.gov/pubmed/35046962 http://dx.doi.org/10.3389/fimmu.2021.811364 |
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