Antibiotic use differentially affects the risk of anti-drug antibody formation during anti-TNFα therapy in inflammatory bowel disease patients: a report from the epi-IIRN

OBJECTIVE: Anti-drug antibodies (ADA) to anti-tumour necrosis factor (anti-TNF) therapy drive treatment loss of response. An association between intestinal microbial composition and response to anti-TNF therapy was noted. We therefore aimed to assess the implications of antibiotic treatments on ADA...

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Detalles Bibliográficos
Autores principales: Gorelik, Yuri, Freilich, Shay, Gerassy-Vainberg, Shiran, Pressman, Sigal, Friss, Chagit, Blatt, Alexandera, Focht, Gili, Weisband, Yiska Loewenberg, Greenfeld, Shira, Kariv, Revital, Lederman, Nathan, Dotan, Iris, Geva-Zatorsky, Naama, Shen-Orr, Shai Shlomo, Kashi, Yechezkel, Chowers, Yehuda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Inflammatory Bowel Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762017/
https://www.ncbi.nlm.nih.gov/pubmed/34344783
http://dx.doi.org/10.1136/gutjnl-2021-325185

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