Cargando…

Predicting 1-Hour Thrombolysis Effect of r-tPA in Patients With Acute Ischemic Stroke Using Machine Learning Algorithm

Background: Thrombolysis with r-tPA is recommended for patients after acute ischemic stroke (AIS) within 4.5 h of symptom onset. However, only a few patients benefit from this therapeutic regimen. Thus, we aimed to develop an interpretable machine learning (ML)–based model to predict the thrombolysi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhu, Bin, Zhao, Jianlei, Cao, Mingnan, Du, Wanliang, Yang, Liuqing, Su, Mingliang, Tian, Yue, Wu, Mingfen, Wu, Tingxi, Wang, Manxia, Zhao, Xingquan, Zhao, Zhigang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762247/ https://www.ncbi.nlm.nih.gov/pubmed/35046804 http://dx.doi.org/10.3389/fphar.2021.759782

Ejemplares similares

Levels of Fibrin Degradation Products at Admission With Acute Ischemic Stroke Correlate With the NIH Stroke Scale Score 1 h After Intravenous Thrombolysis
por: Zhu, Bin, et al.
Publicado: (2021)

Cost-Effectiveness of Thrombolysis within 4.5 Hours of Acute Ischemic Stroke in China
por: Pan, Yuesong, et al.
Publicado: (2014)

The safety and efficacy of tPA intravenous thrombolysis for treating acute ischemic stroke patients with a history of cerebral hemorrhage
por: Zhao, Guang-jian, et al.
Publicado: (2019)

Outcomes of Patients Requiring Blood Pressure Control Before Thrombolysis with tPA for Acute Ischemic Stroke
por: Darger, Bryan, et al.
Publicado: (2015)

Analyses on safety and efficacy of non-standard dose of r-tPA in intravenous thrombolysis-treated AIS patients
por: Yuan, Jiawen, et al.
Publicado: (2022)

Successful use of tPA for thrombolysis in COVID related ARDS: a case series
por: Goyal, Abhishek, et al.
Publicado: (2020)

tPA or not tPA? Lysis therapy in the setting of COVID‐19 and ECMO
por: Cromartie, Anjelica, et al.
Publicado: (2022)

Elevated plasma syndecan-1 as glycocalyx injury marker predicts unfavorable outcomes after rt-PA intravenous thrombolysis in acute ischemic stroke
por: Zhao, Fangfang, et al.
Publicado: (2022)

The Relationship of the Type of Intracerebral Hemorrhage to Early Disease Evolution and Long-Term Prognosis After r-tPA Thrombolysis
por: Yang, Ting, et al.
Publicado: (2021)

Intravenous tPA for Acute Ischemic Stroke in Patients with COVID-19
por: Carneiro, Thiago, et al.
Publicado: (2020)

Association Between the Change of Coagulation Parameters and Clinical Prognosis in Acute Ischemic Stroke Patients After Intravenous Thrombolysis With rt-PA
por: Wang, Yu, et al.
Publicado: (2021)

Intra-Arterial Thrombolysis after Full-Dose Intravenous tPA via the "Drip and Ship" Approach in Patients with Acute Ischemic Stroke: Preliminary Report
por: Park, Man-Seok, et al.
Publicado: (2011)

Hemi Orolingual Angioedema after tPA Administration for Acute Ischemic Stroke
por: Madden, Bryan, et al.
Publicado: (2015)

tPA Helpers in the Treatment of Acute Ischemic Stroke: Are They Ready for Clinical Use?
por: Kim, Jong S.
Publicado: (2019)

Intravenous thrombolysis with 0.65 mg/kg r-tPA may be optimal for Chinese mild-to-moderate stroke
por: Cui, Yu, et al.
Publicado: (2022)

To tPA or Not to tPA: Two Medical-Legal Misadventures of Diagnosing a Cerebrovascular Accident as a Stroke Mimic
por: Moore, Malia J., et al.
Publicado: (2019)

Antiplatelet therapy within 24 hours of tPA: lessons learned from patients requiring combined thrombectomy and stenting for acute ischemic stroke
por: Brandel, Michael G., et al.
Publicado: (2020)

Retrospective study of Heparin Administration for Ischemic Stroke when there is an IV-tPA Contraindication
por: Hakma, Zakaria, et al.
Publicado: (2014)

Institutional Incidence of Severe tPA-Induced Angioedema in Ischemic Cerebral Vascular Accidents
por: Sczepanski, Matthew, et al.
Publicado: (2018)

Cervical carotid occlusion in acute ischemic stroke: Should we give tPA?
por: Elder, Theresa A., et al.
Publicado: (2022)

Early Abrogation of Gelatinase Activity Extends the Time Window for tPA Thrombolysis after Embolic Focal Cerebral Ischemia in Mice
por: Chen, Shanyan, et al.
Publicado: (2018)

Expression of uPA, tPA, and PAI-1 in Calcified Aortic Valves
por: Kochtebane, Najlah, et al.
Publicado: (2014)

Double-Gene Copromoting Expression Analysis in tPA/GH Transgenic Goat Mammary Epithelial Cells and Thrombolytic Activity of tPA In Vitro
por: Song, Shaozheng, et al.
Publicado: (2022)

Provider perceptions of barriers to the emergency use of tPA for Acute Ischemic Stroke: A qualitative study
por: Meurer, William J, et al.
Publicado: (2011)

Angioedema Secondary to tPA Use in Acute Ischemic Stroke Patient with Hypertension: A Case Report
por: Kim, Chris, et al.
Publicado: (2021)

Thrombolytic tPA-induced hemorrhagic transformation of ischemic stroke is mediated by PKCβ phosphorylation of occludin
por: Goncalves, Andreia, et al.
Publicado: (2022)

Unintentional intramuscular administration of tPA/DNase for pleural infection
por: Popowicz, Natalia, et al.
Publicado: (2014)

Exosome-Coated tPA/Catalase Nanoformulation for Thrombolytic Therapy
por: Khalil, Sara, et al.
Publicado: (2023)

l-Palmitoylcarnitine potentiates plasmin and tPA to inhibit thrombosis
por: Yang, Juan, et al.
Publicado: (2023)

Drug-Induced Cardiotoxicity in Children During the Past 30 Years: A Bibliometric Study and Visualization Analysis
por: Wu, Mingfen, et al.
Publicado: (2023)

Current perspectives on the use of intravenous recombinant tissue plasminogen activator (tPA) for treatment of acute ischemic stroke
por: Chapman, Sherita N, et al.
Publicado: (2014)

Effect of isoflurane post-treatment on tPA-exaggerated brain injury in a rat ischemic stroke model
por: Kim, Eun Jung, et al.
Publicado: (2015)

Neuroimmunomodulatory effects of transcranial laser therapy combined with intravenous tPA administration for acute cerebral ischemic injury
por: Peplow, Philip V.
Publicado: (2015)

Ischemic post-conditioning is neuroprotective even at delayed tPA administration after embolic stroke in female rats
por: Mohammadi, Mohadeseh, et al.
Publicado: (2021)

Interferon-β modulates microglial polarization to ameliorate delayed tPA-exacerbated brain injury in ischemic stroke
por: Kuo, Ping-Chang, et al.
Publicado: (2023)

Solitaire™ with the Intention for Thrombectomy as Primary Endovascular Treatment for Acute Ischemic Stroke (SWIFT PRIME) trial: protocol for a randomized, controlled, multicenter study comparing the Solitaire revascularization device with IV tPA with IV tPA alone in acute ischemic stroke
por: Saver, Jeffrey L, et al.
Publicado: (2015)

Treating ischaemic stroke with intravenous tPA beyond 4.5 hours under the guidance of a MRI DWI/T2WI mismatch was safe and effective
por: Bai, Qing-ke, et al.
Publicado: (2019)

Safety and Efficacy of Otaplimastat in Patients with Acute Ischemic Stroke Requiring tPA (SAFE‐TPA): A Multicenter, Randomized, Double‐Blind, Placebo‐Controlled Phase 2 Study
por: Kim, Jong S., et al.
Publicado: (2019)

Synergy of Combined tPA-Edaravone Therapy in Experimental Thrombotic Stroke
por: Sun, Yu-Yo, et al.
Publicado: (2014)

Impacts of tissue-type plasminogen activator (tPA) on neuronal survival
por: Chevilley, Arnaud, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_kdvigrvidc44bisielhku6s3oi