Cargando…
Inhibitory Control in Children 4–10 Years of Age: Evidence From Functional Near-Infrared Spectroscopy Task-Based Observations
Executive function (EF) is essential to child development, with associated skills beginning to emerge in the first few years of life and continuing to develop into adolescence and adulthood. The prefrontal cortex (PFC), which follows a neurodevelopmental timeline similar to EF, plays an important ro...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762317/ https://www.ncbi.nlm.nih.gov/pubmed/35046786 http://dx.doi.org/10.3389/fnhum.2021.798358 |
_version_ | 1784633736184201216 |
---|---|
author | Zhou, Xin Planalp, Elizabeth M. Heinrich, Lauren Pletcher, Colleen DiPiero, Marissa Alexander, Andrew L. Litovsky, Ruth Y. Dean, Douglas C. |
author_facet | Zhou, Xin Planalp, Elizabeth M. Heinrich, Lauren Pletcher, Colleen DiPiero, Marissa Alexander, Andrew L. Litovsky, Ruth Y. Dean, Douglas C. |
author_sort | Zhou, Xin |
collection | PubMed |
description | Executive function (EF) is essential to child development, with associated skills beginning to emerge in the first few years of life and continuing to develop into adolescence and adulthood. The prefrontal cortex (PFC), which follows a neurodevelopmental timeline similar to EF, plays an important role in the development of EF. However, limited research has examined prefrontal function in young children due to limitations of currently available neuroimaging techniques such as functional resonance magnetic imaging (fMRI). The current study developed and applied a multimodal Go/NoGo task to examine the EF component of inhibitory control in children 4–10 years of age. Cortical activity was measured using a non-invasive and child-friendly neuroimaging technique – functional near-infrared spectroscopy (fNIRS). Children’s response accuracy and reaction times were captured during the fNIRS session and compared with responses obtained using the standardized assessments from NIH Toolbox cognition battery. Results showed significant correlations between the behavioral measures during the fNIRS session and the standardized EF assessments, in line with our expectations. Results from fNIRS measures demonstrated a significant, age-independent effect of inhibitory control (IC) in the right PFC (rPFC), and an age-dependent effect in the left orbitofrontal cortex (lOFC), consistent with results in previous studies using fNIRS and fMRI. Thus, the new task designed for fNIRS was suitable for examining IC in young children, and results showed that fNIRS measures can reveal prefrontal IC function. |
format | Online Article Text |
id | pubmed-8762317 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-87623172022-01-18 Inhibitory Control in Children 4–10 Years of Age: Evidence From Functional Near-Infrared Spectroscopy Task-Based Observations Zhou, Xin Planalp, Elizabeth M. Heinrich, Lauren Pletcher, Colleen DiPiero, Marissa Alexander, Andrew L. Litovsky, Ruth Y. Dean, Douglas C. Front Hum Neurosci Human Neuroscience Executive function (EF) is essential to child development, with associated skills beginning to emerge in the first few years of life and continuing to develop into adolescence and adulthood. The prefrontal cortex (PFC), which follows a neurodevelopmental timeline similar to EF, plays an important role in the development of EF. However, limited research has examined prefrontal function in young children due to limitations of currently available neuroimaging techniques such as functional resonance magnetic imaging (fMRI). The current study developed and applied a multimodal Go/NoGo task to examine the EF component of inhibitory control in children 4–10 years of age. Cortical activity was measured using a non-invasive and child-friendly neuroimaging technique – functional near-infrared spectroscopy (fNIRS). Children’s response accuracy and reaction times were captured during the fNIRS session and compared with responses obtained using the standardized assessments from NIH Toolbox cognition battery. Results showed significant correlations between the behavioral measures during the fNIRS session and the standardized EF assessments, in line with our expectations. Results from fNIRS measures demonstrated a significant, age-independent effect of inhibitory control (IC) in the right PFC (rPFC), and an age-dependent effect in the left orbitofrontal cortex (lOFC), consistent with results in previous studies using fNIRS and fMRI. Thus, the new task designed for fNIRS was suitable for examining IC in young children, and results showed that fNIRS measures can reveal prefrontal IC function. Frontiers Media S.A. 2022-01-03 /pmc/articles/PMC8762317/ /pubmed/35046786 http://dx.doi.org/10.3389/fnhum.2021.798358 Text en Copyright © 2022 Zhou, Planalp, Heinrich, Pletcher, DiPiero, Alexander, Litovsky and Dean. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Human Neuroscience Zhou, Xin Planalp, Elizabeth M. Heinrich, Lauren Pletcher, Colleen DiPiero, Marissa Alexander, Andrew L. Litovsky, Ruth Y. Dean, Douglas C. Inhibitory Control in Children 4–10 Years of Age: Evidence From Functional Near-Infrared Spectroscopy Task-Based Observations |
title | Inhibitory Control in Children 4–10 Years of Age: Evidence From Functional Near-Infrared Spectroscopy Task-Based Observations |
title_full | Inhibitory Control in Children 4–10 Years of Age: Evidence From Functional Near-Infrared Spectroscopy Task-Based Observations |
title_fullStr | Inhibitory Control in Children 4–10 Years of Age: Evidence From Functional Near-Infrared Spectroscopy Task-Based Observations |
title_full_unstemmed | Inhibitory Control in Children 4–10 Years of Age: Evidence From Functional Near-Infrared Spectroscopy Task-Based Observations |
title_short | Inhibitory Control in Children 4–10 Years of Age: Evidence From Functional Near-Infrared Spectroscopy Task-Based Observations |
title_sort | inhibitory control in children 4–10 years of age: evidence from functional near-infrared spectroscopy task-based observations |
topic | Human Neuroscience |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762317/ https://www.ncbi.nlm.nih.gov/pubmed/35046786 http://dx.doi.org/10.3389/fnhum.2021.798358 |
work_keys_str_mv | AT zhouxin inhibitorycontrolinchildren410yearsofageevidencefromfunctionalnearinfraredspectroscopytaskbasedobservations AT planalpelizabethm inhibitorycontrolinchildren410yearsofageevidencefromfunctionalnearinfraredspectroscopytaskbasedobservations AT heinrichlauren inhibitorycontrolinchildren410yearsofageevidencefromfunctionalnearinfraredspectroscopytaskbasedobservations AT pletchercolleen inhibitorycontrolinchildren410yearsofageevidencefromfunctionalnearinfraredspectroscopytaskbasedobservations AT dipieromarissa inhibitorycontrolinchildren410yearsofageevidencefromfunctionalnearinfraredspectroscopytaskbasedobservations AT alexanderandrewl inhibitorycontrolinchildren410yearsofageevidencefromfunctionalnearinfraredspectroscopytaskbasedobservations AT litovskyruthy inhibitorycontrolinchildren410yearsofageevidencefromfunctionalnearinfraredspectroscopytaskbasedobservations AT deandouglasc inhibitorycontrolinchildren410yearsofageevidencefromfunctionalnearinfraredspectroscopytaskbasedobservations |