Transcriptomic Profiling in Mice With CB1 receptor Deletion in Primary Sensory Neurons Suggests New Analgesic Targets for Neuropathic Pain

Type 1 and type 2 cannabinoid receptors (CB1 and CB2, respectively) mediate cannabinoid-induced analgesia. Loss of endogenous CB1 is associated with hyperalgesia. However, the downstream targets affected by ablation of CB1 in primary sensory neurons remain unknown. In the present study, we hypothesi...

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Detalles Bibliográficos
Autores principales: Liu, Yongmin, Jia, Min, Wu, Caihua, Zhang, Hong, Chen, Chao, Ge, Wenqiang, Wan, Kexing, Lan, Yuye, Liu, Shiya, Li, Yuanheng, Fang, Mengyue, He, Jiexi, Pan, Hui-Lin, Si, Jun-Qiang, Li, Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762320/
https://www.ncbi.nlm.nih.gov/pubmed/35046811
http://dx.doi.org/10.3389/fphar.2021.781237

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