A Multiscale, Systems-Level, Neuropharmacological Model of Cortico-Basal Ganglia System for Arm Reaching Under Normal, Parkinsonian, and Levodopa Medication Conditions

In order to understand the link between substantia nigra pars compacta (SNc) cell loss and Parkinson's disease (PD) symptoms, we developed a multiscale computational model that can replicate the symptoms at the behavioural level by incorporating the key cellular and molecular mechanisms underly...

Descripción completa

Detalles Bibliográficos
Autores principales: Nair, Sandeep Sathyanandan, Muddapu, Vignayanandam Ravindernath, Chakravarthy, V. Srinivasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762321/
https://www.ncbi.nlm.nih.gov/pubmed/35046787
http://dx.doi.org/10.3389/fncom.2021.756881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762321/
https://www.ncbi.nlm.nih.gov/pubmed/35046787
http://dx.doi.org/10.3389/fncom.2021.756881

Ejemplares similares