Contribution of Rare and Low-Frequency Variants to Multiple Sclerosis Susceptibility in the Italian Continental Population

Genome-wide association studies identified over 200 risk loci for multiple sclerosis (MS) focusing on common variants, which account for about 50% of disease heritability. The goal of this study was to investigate whether low-frequency and rare functional variants, located in MS-established associat...

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Detalles Bibliográficos
Autores principales: Clarelli, Ferdinando, Barizzone, Nadia, Mangano, Eleonora, Zuccalà, Miriam, Basagni, Chiara, Anand, Santosh, Sorosina, Melissa, Mascia, Elisabetta, Santoro, Silvia, Guerini, Franca Rosa, Virgilio, Eleonora, Gallo, Antonio, Pizzino, Alessandro, Comi, Cristoforo, Martinelli, Vittorio, Comi, Giancarlo, De Bellis, Gianluca, Leone, Maurizio, Filippi, Massimo, Esposito, Federica, Bordoni, Roberta, Martinelli Boneschi, Filippo, D'Alfonso, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762330/
https://www.ncbi.nlm.nih.gov/pubmed/35047017
http://dx.doi.org/10.3389/fgene.2021.800262

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