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Violations of proportional hazard assumption in Cox regression model of transcriptomic data in TCGA pan-cancer cohorts

BACKGROUND: Cox proportional hazard regression (CPH) model relies on the proportional hazard (PH) assumption: the hazard of variables is independent of time. CPH has been widely used to identify prognostic markers of the transcriptome. However, the comprehensive investigation on PH assumption in tra...

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Detalles Bibliográficos
Autores principales: Zeng, Zihang, Gao, Yanping, Li, Jiali, Zhang, Gong, Sun, Shaoxing, Wu, Qiuji, Gong, Yan, Xie, Conghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762368/
https://www.ncbi.nlm.nih.gov/pubmed/35070171
http://dx.doi.org/10.1016/j.csbj.2022.01.004

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