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Violations of proportional hazard assumption in Cox regression model of transcriptomic data in TCGA pan-cancer cohorts
BACKGROUND: Cox proportional hazard regression (CPH) model relies on the proportional hazard (PH) assumption: the hazard of variables is independent of time. CPH has been widely used to identify prognostic markers of the transcriptome. However, the comprehensive investigation on PH assumption in tra...
Autores principales: | Zeng, Zihang, Gao, Yanping, Li, Jiali, Zhang, Gong, Sun, Shaoxing, Wu, Qiuji, Gong, Yan, Xie, Conghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762368/ https://www.ncbi.nlm.nih.gov/pubmed/35070171 http://dx.doi.org/10.1016/j.csbj.2022.01.004 |
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