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Innate immune sensing of influenza A viral RNA through IFI16 promotes pyroptotic cell death

Programmed cell death pathways are triggered by various stresses or stimuli, including viral infections. The mechanism underlying the regulation of these pathways upon Influenza A virus (IAV) infection is not well characterized. We report that a cytosolic DNA sensor IFI16 is essential for the activa...

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Detalles Bibliográficos
Autores principales:	Mishra, Shalabh, Raj, Athira S., Kumar, Akhilesh, Rajeevan, Ashwathi, Kumari, Puja, Kumar, Himanshu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762390/ https://www.ncbi.nlm.nih.gov/pubmed/35072006 http://dx.doi.org/10.1016/j.isci.2021.103714

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