Clusterin is involved in mediating the metabolic function of adipose SIRT1

SIRT1 is a metabolic sensor regulating energy homeostasis. The present study revealed that mice with selective overexpression of human SIRT1 in adipose tissue (Adipo-SIRT1) were protected from high-fat diet (HFD)-induced metabolic abnormalities. Adipose SIRT1 was enriched at mitochondria-ER contacts...

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Detalles Bibliográficos
Autores principales: Zhang, Pengcheng, Konja, Daniels, Zhang, Yiwei, Xu, Aimin, Lee, In-Kyu, Jeon, Jae-Han, Bashiri, Ghader, Mitra, Alok, Wang, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8762396/
https://www.ncbi.nlm.nih.gov/pubmed/35072003
http://dx.doi.org/10.1016/j.isci.2021.103709

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